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PCDHB6 Antibody, ALEXA FLUOR 488

PCDHB6 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, PCDHB6 Polyclonal Antibody
Also known asAnti-PCDHB6 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPCDHB6
SpecificityThis is a highly specific antibody against PCDHB6
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PCDHB6
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen As a result, PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain, There are three protocadherin gene clusters, Unlike most protocadherin-beta proteins, Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, all of which contain multiple tandemly arranged genes, beta and gamma, designated alpha, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs, suggesting a role in signal transduction cascade events, Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms PCDH-BETA6
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PCDHB6 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetPCDHB6
Short namePCDHB6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, protocadherin b 6 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target PCDHB6 and IDBG-49974 and ENSG00000113211 and 56130, PCDHB6 and IDBG-648650 and ENSBTAG00000047478 and 786512, Pcdhb13 and IDBG-139928 and ENSMUSG00000047307 and 93884, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007399 and nervous system development and biological process this GO :0007416 and synapse assembly and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016339 and calcium-dependent cell-cell adhesion and biological process, this GO :0005509: calcium ion binding, this GO :0005509: calcium ion binding, protocadherin beta 6
Identity 8691
Gene PCDHB6
Long gene name protocadherin beta 6
Locus 5q31, 3
Discovery year 2000-06-28
GenBank acession AF152499
Entrez gene record 56130
Pubmed identfication 10380929
RefSeq identity NM_018939
Classification Clustered protocadherins
Havana BLAST/BLAT OTTHUMG00000129623

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