PCNA (1655CT506.10.26) Monoclonal Antibody

PCNA (1655CT506.10.26) Monoclonal Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 281

Size 0.1ml

Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit

Long name	10, 26) Monoclonal Antibody, PCNA (1655CT506
Also known as	10, 26) Monoclonal Antibody, PCNA (1655CT506
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	PCNA
Specificity	This is a highly specific antibody against PCNA
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Monoclonal
Clone number	10, 1655CT506, 26
Source	This PCNA antibody is generated from a mouse immunized with a recombinant protein of human PCNA
Gene ID number	5111
Swiss Prot	P12004
Tested Applications	FCM, IHC-P, WB
Recommended dilutions	FC(1:25), WB(1:2000), IHC-P(1:25)
Cross reactivity	Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	APEX2 activities, Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, Has to be loaded onto DNA in order to be able to stimulate APEX2, Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways (PubMed:24939902), but not apurinic-apyrimidinic (AP) endonuclease, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion, Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	Cyclin, PCNA, Proliferating cell nuclear antigen, ATLD2
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About	Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target	10, 26) Monoclonal, PCNA (1655CT506
Short name	10, 26) Monoclonal Antibody, PCNA (1655CT506
Technique	Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name	10, 26) monoclonal (Antibody to), PCNA (1655CT506
Alternative technique	antibodies
Identity	8729
Gene	PCNA
Long gene name	proliferating cell nuclear antigen
Locus	20p12, 3
Discovery year	1990-01-15
GenBank acession	J04718
Entrez gene record	5111
Pubmed identfication	2565339
Havana BLAST/BLAT	OTTHUMG00000031798

PCNA (1655CT506.10.26) Monoclonal Antibody

PCNA (1655CT506.10.26) Monoclonal Antibody size: 0.1ml 281

Similar products

Subscribe to our Newsletter