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PCPTP1 Antibody, Biotin Conjugated

PCPTP1 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, PCPTP1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPCPTP1
SpecificityThis is a highly specific antibody against PCPTP1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human PCPTP1
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ECPTP, Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, PTPBR7 or PTPRQ, The alpha form is localized to the cell membrane, Three isoforms of PCPTP1 exist and are designated alpha, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), beta and gamma, cell differentiation, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm, oncogenic transformation and the mitotic cycle, thereby rendering them inactive, while the beta and gamma forms are localized to the perinuclear areas within the cytoplasm, The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms PTPBR7 PTP-SL EC-PTP PCPTP1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPCPTP1 Conjugated
Short name Conjugated, PCPTP1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, PCPTP1 (Antibody to)
Alternative techniqueantibodies
Identity 9680
Gene PTPRR
Long gene name protein tyrosine phosphatase, receptor type R
Synonyms gene PTPRQ
Locus 12q15
Discovery year 1999-10-28
GenBank acession D64053
Entrez gene record 5801
Pubmed identfication 7557444 10393441
RefSeq identity NM_002849
Classification Protein tyrosine phosphatases, receptor type
Havana BLAST/BLAT OTTHUMG00000169502

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