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PCPTP1 Antibody, FITC Conjugated

PCPTP1 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, PCPTP1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPCPTP1
SpecificityThis is a highly specific antibody against PCPTP1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human PCPTP1
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ECPTP, Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, PTPBR7 or PTPRQ, The alpha form is localized to the cell membrane, Three isoforms of PCPTP1 exist and are designated alpha, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), beta and gamma, cell differentiation, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm, oncogenic transformation and the mitotic cycle, thereby rendering them inactive, while the beta and gamma forms are localized to the perinuclear areas within the cytoplasm, The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms PTPBR7 PTP-SL EC-PTP PCPTP1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPCPTP1 Conjugated
Short name FITC Conjugated, PCPTP1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PCPTP1 (Antibody to)
Alternative techniqueantibodies
Identity 9680
Gene PTPRR
Long gene name protein tyrosine phosphatase, receptor type R
Synonyms gene PTPRQ
Locus 12q15
Discovery year 1999-10-28
GenBank acession D64053
Entrez gene record 5801
Pubmed identfication 7557444 10393441
RefSeq identity NM_002849
Classification Protein tyrosine phosphatases, receptor type
Havana BLAST/BLAT OTTHUMG00000169502

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