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PCSK9 Antibody

PCSK9 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPCSK9
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB, FACS
Recommended dilutionsFlow Cytometry: 1:25, IHC (Paraffin): 1:25, Western blot: 1:1000
NotesTitration of the PCSK9 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis PCSK9 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q8NBP7
PurityAntigen affinity
Description The protein may function as a proprotein convertase, The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons, This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family
ImmunogenA portion of amino acids 144-173 from the human protein was used as the immunogen for this PCSK9 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PCSK9 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPCSK9
Short namePCSK9 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameproprotein convertase subtilisin/kexin classification 9 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Extracellular, PCSK9 and IDBG-99082 and ENSG00000169174 and 255738, Pcsk9 and IDBG-170186 and ENSMUSG00000044254 and 100102, this GO :0001822 and kidney development and biological process this GO :0001889 and liver development and biological process this GO :0001920 and negative regulation of receptor recycling and biological process this GO :0002092 and positive regulation of receptor internalization and biological process this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005791 and rough endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0006641 and triglyceride metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007041 and lysosomal transport and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0009267 and cellular response to starvation and biological process this GO :0009986 and cell surface and cellular component this GO :0010469 and regulation of receptor activity and biological process this GO :0010989 and negative regulation of low-density lipoprotein particle clearance and biological process this GO :0016485 and protein processing and biological process this GO :0016540 and protein autoprocessing and biological process this GO :0019871 and sodium channel inhibitor activity and molecular function this GO :0022008 and neurogenesis and biological process this GO :0030134 and ER to this GO lgi transport vesicle and cellular component this GO :0030169 and low-density lipoprotein particle binding and molecular function this GO :0030182 and neuron differentiation and biological process this GO :0031232 and extrinsic component of external side of plasma membrane and cellular component this GO :0032799 and low-density lipoprotein receptor particle metabolic process and biological process this GO :0032802 and low-density lipoprotein particle receptor catabolic process and biological process this GO :0032803 and regulation of low-density lipoprotein particle receptor catabolic process and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0034185 and apolipoprotein binding and molecular function this GO :0034189 and very-low-density lipoprotein particle binding and molecular function this GO :0034190 and apolipoprotein receptor binding and molecular function this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0043621 and protein self-association and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050750 and low-density lipoprotein particle receptor binding and molecular function this GO :0070326 and very-low-density lipoprotein particle receptor binding and molecular function, this GO :0004252: serine-type endopeptidase activity, this GO :0004252: serine-type endopeptidase activity and also this GO :0005515: protein binding and also this GO :0019871: sodium channel inhibitor activity and also this GO :0030169: low-density lipoprotein particle binding and also this GO :0034185: apolipoprotein binding and also this GO :0034189: very-low-density lipoprotein particle binding and also this GO :0034190: apolipoprotein receptor binding and also this GO :0043621: protein self-association and also this GO :0044822: poly(A) RNA binding and also this GO :0050750: low-density lipoprotein particle receptor binding and also this GO :0070326: very-low-density lipoprotein particle receptor binding, this GO :0005515: protein binding, this GO :0019871: sodium channel inhibitor activity, this GO :0030169: low-density lipoprotein particle binding, this GO :0034185: apolipoprotein binding, this GO :0034189: very-low-density lipoprotein particle binding, this GO :0034190: apolipoprotein receptor binding, this GO :0043621: protein self-association, this GO :0044822: poly(A) RNA binding, this GO :0050750: low-density lipoprotein particle receptor binding, this GO :0070326: very-low-density lipoprotein particle receptor binding, very-low-density lipoprotein particle receptor binding, proprotein convertase subtilisin/kexin type 9
Identity 20001
Gene PCSK9
Long gene name proprotein convertase subtilisin/kexin type 9
Synonyms gene HCHOLA3
Synonyms gene name autosomal dominant 3 , hypercholesterolemia
Synonyms NARC-1 FH3
Locus 1p32, 3
Discovery year 2003-05-13
GenBank acession AX207686
Entrez gene record 255738
Pubmed identfication 12552133 12730697
RefSeq identity NM_174936
Classification Proprotein convertase subtilisin/kexin family
Havana BLAST/BLAT OTTHUMG00000008136
Locus Specific Databases British Heart Foundation LRG_275

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