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PDCD1 / PD-1 Antibody

PDCD1 / PD-1 Antibody size: 0.1mg 372

Supplier NJS POLY
Price 372
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration05% sodium azide, 1 mg/ml BSA (US sourced) and 0, 2 mg/ml in 1X PBS with 0
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPDCD1 / PD-1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity , Due to limited knowledge and inability to test the antibody against all known species, Other species not tested, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications FACS, IF, IHC-P
Recommended dilutions1ml, 5-1ug/10e6 cells in 0, FACS: 0, Immunofluorescence: 1-2ug/ml, Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
NotesTitering of the PD1 antibody may be required for optimal performance
Intented useThis PD1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q15116
PurityPurified by protein A Affinity Chromatography
Description Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm, B-cells, It is expressed on activated T-cells, PDCD1 is expressed by few B-cells, Unlike CD10 and BCL6, also called PD1 and CD279, and myeloid cells, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma, PDCD1 (Programmed cell death-1 protein)
ImmunogenA full-length human protein was used as the immunogen for the PD1 antibody
StorageStore the PD1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide)
Localization cytoplasmic, Cell surface &
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPDCD1 / PD-1
Short namePDCD1 / PD-1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameprogrammed cellular death 1 / PD-1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CD279 and hPD-1 and hPD-l and hSLE1 and PD-1 and PD1 and SLEB2, Cell surfaces, PDCD1 and IDBG-642702 and ENSBTAG00000011543 and 613842, PDCD1 and IDBG-85346 and ENSG00000188389 and 5133, Pdcd1 and IDBG-184148 and ENSMUSG00000026285 and 18566, protein binding, this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006959 and humoral immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0031295 and T cell costimulation and biological process this GO :0045087 and innate immune response and biological process, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0005515: protein binding, this GO :0005515: protein binding, programmed cell death 1
Identity 8760
Gene PDCD1
Long gene name programmed cell death 1
Synonyms gene SLEB2
Synonyms gene name systemic lupus erythematosus susceptibility 2
Synonyms CD279 PD1 hSLE1 PD-1
Locus 2q37, 3
Discovery year 1994-05-24
GenBank acession AY206416
Entrez gene record 5133
Pubmed identfication 7851902 12402038
RefSeq identity NM_005018
Classification CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000151342

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