| Long name | PDCD4 Primary Polyclonal Antibody |
| Also known as | PDCD4 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PDCD4 |
| Specificity | This is a highly specific antibody against PDCD4 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 30-80/469 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDCD4 |
| Gene ID number | 27250 |
| Swiss Prot | Q53EL6 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binds RNA (By similarity), Down-regulates the expression of MAP4K1, Inhibits the helicase activity of EIF4A, Inhibits tumor promoter-induced neoplastic transformation, MAPK85 activation and consequent JUN-dependent transcription, May excert its function by hindering the interaction between EIF4A1 and EIF4G, May play a role in apoptosis, Modulates the activation of JUN kinase, Tumor suppressor, namely, thus inhibiting events important in driving invasion, Inhibits translation initiation and cap-dependent translation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Neoplastic transformation inhibitor protein, Nuclear antigen H731-like, PDCD4, Programmed cell death protein 4, Protein 197/15a, H731 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PDCD4 |
| Short name | PDCD4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | programmed cellular death 4 (neoplastic transformation inhibitor) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process, PDCD4 and IDBG-639738 and ENSBTAG00000019434 and 506724, PDCD4 and IDBG-89535 and ENSG00000150593 and 100616113, Pdcd4 and IDBG-176913 and ENSMUSG00000024975 and 18569, nuclei, protein binding, this GO :0003723 and RNA binding and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007569 and cell aging and biological process this GO :0043508 and negative regulation of JUN kinase activity and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, this GO :0003723: RNA binding, this GO :0003723: RNA binding and also this GO :0005488: binding and also this GO :0005515: protein binding, this GO :0005488: binding, this GO :0005515: protein binding, 27250, programmed cell death 4 (neoplastic transformation inhibitor) |
| Identity | 8763 |
| Gene | PDCD4 |
| Long gene name | programmed cell death 4 |
| Synonyms gene name | programmed cell death 4 (neoplastic transformation inhibitor) |
| Synonyms | H731 |
| Synonyms name | nuclear antigen H731 |
| Locus | 10q25, 2 |
| Discovery year | 2000-05-10 |
| GenBank acession | U83908 |
| Entrez gene record | 27250 |
| Pubmed identfication | 9759869 |
| RefSeq identity | NM_014456 |
| Havana BLAST/BLAT | OTTHUMG00000019048 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue