Name : PDCD4 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6886107781
| Long name | ALEXA FLUOR 488 Conjugated, PDCD4 Polyclonal Antibody |
| Also known as | Anti-PDCD4 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PDCD4 |
| Specificity | This is a highly specific antibody against PDCD4 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 30-80/469 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDCD4 |
| Gene ID Number | 27250 |
| Swiss Prot | Q53EL6 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Binds RNA (By similarity), Down-regulates the expression of MAP4K1, Inhibits the helicase activity of EIF4A, Inhibits tumor promoter-induced neoplastic transformation, MAPK85 activation and consequent JUN-dependent transcription, May excert its function by hindering the interaction between EIF4A1 and EIF4G, May play a role in apoptosis, Modulates the activation of JUN kinase, Tumor suppressor, namely, thus inhibiting events important in driving invasion, Inhibits translation initiation and cap-dependent translation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | H731 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PDCD4 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | PDCD4 |
| Short name | PDCD4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, programmed cellular death 4 (neoplastic transformation inhibitor) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process, PDCD4 and IDBG-639738 and ENSBTAG00000019434 and 506724, PDCD4 and IDBG-89535 and ENSG00000150593 and 100616113, Pdcd4 and IDBG-176913 and ENSMUSG00000024975 and 18569, nuclei, protein binding, this GO :0003723 and RNA binding and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007569 and cell aging and biological process this GO :0043508 and negative regulation of JUN kinase activity and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, this GO :0003723: RNA binding, this GO :0003723: RNA binding and also this GO :0005488: binding and also this GO :0005515: protein binding, this GO :0005488: binding, this GO :0005515: protein binding, 27250, programmed cell death 4 (neoplastic transformation inhibitor) |
| Identity | 8763 |
| Gene | PDCD4 |
| Long gene name | programmed cell death 4 |
| Synonyms gene name | programmed cell death 4 (neoplastic transformation inhibitor) |
| Synonyms name | nuclear antigen H731 |
| Locus | 10q25, 2 |
| Discovery year | 2000-05-10 |
| GenBank acession | U83908 |
| Entrez gene record | 27250 |
| Pubmed identfication | 9759869 |
| RefSeq identity | NM_014456 |
| Havana BLAST/BLAT | OTTHUMG00000019048 |