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PDCD4 Antibody, Biotin Conjugated

PDCD4 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, PDCD4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPDCD4
SpecificityThis is a highly specific antibody against PDCD4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range30-80/469
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human PDCD4
Gene ID number27250
Swiss ProtQ53EL6
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binds RNA (By similarity), Down-regulates the expression of MAP4K1, Inhibits the helicase activity of EIF4A, Inhibits tumor promoter-induced neoplastic transformation, MAPK85 activation and consequent JUN-dependent transcription, May excert its function by hindering the interaction between EIF4A1 and EIF4G, May play a role in apoptosis, Modulates the activation of JUN kinase, Tumor suppressor, namely, thus inhibiting events important in driving invasion, Inhibits translation initiation and cap-dependent translation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms H731
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPDCD4 Conjugated
Short name Conjugated, PDCD4 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, programmed cellular death 4 (neoplastic transformation inhibitor) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process, PDCD4 and IDBG-639738 and ENSBTAG00000019434 and 506724, PDCD4 and IDBG-89535 and ENSG00000150593 and 100616113, Pdcd4 and IDBG-176913 and ENSMUSG00000024975 and 18569, nuclei, protein binding, this GO :0003723 and RNA binding and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007569 and cell aging and biological process this GO :0043508 and negative regulation of JUN kinase activity and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, this GO :0003723: RNA binding, this GO :0003723: RNA binding and also this GO :0005488: binding and also this GO :0005515: protein binding, this GO :0005488: binding, this GO :0005515: protein binding, 27250, programmed cell death 4 (neoplastic transformation inhibitor)
Identity 8763
Gene PDCD4
Long gene name programmed cell death 4
Synonyms gene name programmed cell death 4 (neoplastic transformation inhibitor)
Synonyms name nuclear antigen H731
Locus 10q25, 2
Discovery year 2000-05-10
GenBank acession U83908
Entrez gene record 27250
Pubmed identfication 9759869
RefSeq identity NM_014456
Havana BLAST/BLAT OTTHUMG00000019048

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