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PDE4D Antibody, FITC Conjugated

PDE4D Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, PDE4D Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPDE4D
SpecificityThis is a highly specific antibody against PDE4D
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human PDE4D
Gene ID number5144
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background D2, D3, D4 and D5), In CNS all five PDE4D subtype variants are expressed in varying ratios and their activity is regulated in tandem with GPCRs stimulation, MAP kinases and Erk2 phosphorylation that results in rapid change in their enzymatic activities, One or more PDE4D subtype variants are ubiquitously present in all mammalian cells, Other regulatory mechanism involved protein protein interactions with cytoskeletal scaffolding proteins, PDE4D1/D2 mRNA levels rise in response to an increase in cAMP, Peripheral tissues also exhibit differential expression of PDE4D variants, Short term regulation of PDE4D variants involved PKA, Cyclic AMP-dependent phosphodiesterase type D (PDE4D) family is comprise of 5 variants (PDE4D1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPDE4D Conjugated
Short name FITC Conjugated, PDE4D Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PDE4D (Antibody to)
Alternative techniqueantibodies
Identity 8783
Gene PDE4D
Long gene name phosphodiesterase 4D
Synonyms gene DPDE3
Synonyms gene name cAMP-specific , cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3) phosphodiesterase 4D, phosphodiesterase 4D
Synonyms name phosphodiesterase E3 dunce homolog (Drosophila)
Locus 5q11, 1 , 2-q12
Discovery year 1992-06-08
Entrez gene record 5144
Classification Phosphodiesterases
Havana BLAST/BLAT OTTHUMG00000162218

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