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PDGFR beta Antibody (CD140b)

PDGFR beta Antibody (CD140b) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPDGFR beta (CD140b)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IF, WB, IHC
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
Notes Titration of the PDGFR beta antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis PDGFR beta antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P09619
PurityPurified
Description A translocation between chromosomes 5 and 12, ETS, The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, These growth factors are mitogens for cells of mesenchymal origin, all three genes may be implicated in the 5-q syndrome, composed of both platelet-derived growth factor receptor alpha and beta polypeptides, leukemia gene, results in chronic myelomonocytic leukemia, that fuses the gene to that of the translocation, PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family
ImmunogenA portion of amino acids 40-72 from the human protein was used as the immunogen for this CD140b / PDGFR beta antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot the PDGFR beta antibody and store frozen at -20 deg, Store at 4oC for up to one month
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPDGFR beta (CD140b)
Short namePDGFR beta Antibody (CD140b)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePDGFR b (Antibody to) (CD140b)
Alternative techniqueantibodies
Identity 8804
Gene PDGFRB
Long gene name platelet derived growth factor receptor beta
Synonyms gene PDGFR
Synonyms gene name beta polypeptide , platelet-derived growth factor receptor
Synonyms JTK12 CD140b PDGFR1
Locus 5q32
Discovery year 2001-06-22
GenBank acession M21616
Entrez gene record 5159
RefSeq identity NM_002609
Classification I-set domain containing CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000130053

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