| Long name | Cy5, 5 Conjugated, PDGFRA(Tyr849)/PDGFRB(Tyr857) Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PDGFRA Tyr849 + PDGFRB Tyr857 |
| Specificity | This is a highly specific antibody against PDGFRA Tyr849 + PDGFRB Tyr857 |
| Modification | Phosphorylation |
| Modification site | Tyr857 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PDGF Receptor alpha around the phosphorylation site of Tyr849 [SN(p-Y)VS] |
| Gene ID number | 5156 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Both receptors are transmembranous, CD140a antigen), The response of any given cell to PDGF will depend on the types of receptors displayed on the surface and isoforms of PDGF present in the extracellular environment, a 170kD protein, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity, binds all three isoforms of PDGF with high affinity whereas the PDGF Receptor Type B, ligand activated protein tyrosine kinases, which are bound with differential affinities via SH2 domains, which phosphorylate a number of important signal transduction proteins, The PDGF Receptor Type A (Alpha platelet-derived growth factor receptor precursor |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | JTK12 CD140b PDGFR1 |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | PDGFRA(Tyr849)/PDGFRB(Tyr857) Conjugated |
| Short name | Conjugated, PDGFRA(Tyr849)/PDGFRB(Tyr857) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | a polypeptide(Tyr849)/platelet-derived growth factor receptor, b polypeptide(Tyr857) (Antibody to), cyanine 5, 5 coupled, platelet-derived growth factor receptor |
| Alternative technique | antibodies |
| Alternative to gene target | BT, CD140A and PDGFR-2 and PDGFR2 and RHEPDGFRA, CD140B and IBGC4 and IMF1 and JTK12 and PDGFR and PDGFR-1 and PDGFR1, PDGFRA and IDBG-18854 and ENSG00000134853 and 5156, PDGFRA and IDBG-642308 and ENSBTAG00000007173 and 282301, PDGFRB and IDBG-53326 and ENSG00000113721 and 5159, Pdgfra and IDBG-171929 and ENSMUSG00000029231 and 18595, Pdgfrb and IDBG-150834 and ENSMUSG00000024620 and 18596, alpha polypeptide, beta polypeptide, nuclei, nuclei, platelet-derived growth factor receptor, this GO :0001553 and luteinization and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001775 and cell activation and biological process this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005018 and platelet-derived growth factor alpha-receptor activity and molecular function this GO :0005021 and vascular endothelial growth factor-activated receptor activity and molecular function this GO :0005161 and platelet-derived growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005902 and microvillus and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0008210 and estrogen metabolic process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008585 and female this GO nad development and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010544 and negative regulation of platelet activation and biological process this GO :0010863 and positive regulation of phospholipase C activity and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, this GO :0001701 and in utero embryonic development and biological process this GO :0001822 and kidney development and biological process this GO :0001894 and tissue homeostasis and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0004992 and platelet activating factor receptor activity and molecular function this GO :0005017 and platelet-derived growth factor-activated receptor activity and molecular function this GO :0005019 and platelet-derived growth factor beta-receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005161 and platelet-derived growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006024 and glycosaminoglycan biosynthetic process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006807 and nitrogen compound metabolic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009636 and response to toxic substance and biological process this GO :0009986 and cell surface and cellular component this GO :0010863 and positive regulation of phospholipase C activity and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014911 and positive regulation of smooth muscle cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016301 and kinase activity and molecular function this GO :0016324 and apical plasma membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0004871: signal transducer activity and also this GO :0004992: platelet activating factor receptor activity and also this GO :0005017: platelet-derived growth factor-activated receptor activity and also this GO :0005019: platelet-derived growth factor beta-receptor activity and also this GO :0005102: receptor binding and also this GO :0005161: platelet-derived growth factor receptor binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016301: kinase activity and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0005018: platelet-derived growth factor alpha-receptor activity and also this GO :0005021: vascular endothelial growth factor-activated receptor activity and also this GO :0005161: platelet-derived growth factor receptor binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0004871: signal transducer activity, this GO :0004992: platelet activating factor receptor activity, this GO :0005017: platelet-derived growth factor-activated receptor activity, this GO :0005018: platelet-derived growth factor alpha-receptor activity, this GO :0005019: platelet-derived growth factor beta-receptor activity, this GO :0005021: vascular endothelial growth factor-activated receptor activity, this GO :0005102: receptor binding, this GO :0005161: platelet-derived growth factor receptor binding, this GO :0005161: platelet-derived growth factor receptor binding, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0005524: ATP binding, this GO :0016301: kinase activity, this GO :0016772: transferase activity, this GO :0016772: transferase activity, this GO :0019901: protein kinase binding, this GO :0038085: vascular endothelial growth factor binding, this GO :0038085: vascular endothelial growth factor binding, this GO :0042803: protein homodimerization activity, this GO :0043548: phosphatidylinositol 3-kinase binding, this GO :0048407: platelet-derived growth factor binding, this GO :0048407: platelet-derived growth factor binding, transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901: protein kinase binding and also this GO :0038085: vascular endothelial growth factor binding and also this GO :0043548: phosphatidylinositol 3-kinase binding and also this GO :0048407: platelet-derived growth factor binding, transferring phosphorus-containing groups and also this GO :0038085: vascular endothelial growth factor binding and also this GO :0042803: protein homodimerization activity and also this GO :0048407: platelet-derived growth factor binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030325 and adrenal gland development and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031226 and intrinsic component of plasma membrane and cellular component this GO :0032355 and response to estradiol and biological process this GO :0032516 and positive regulation of phosphoprotein phosphatase activity and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0033993 and response to lipid and biological process this GO :0034405 and response to fluid shear stress and biological process this GO :0035441 and cell migration involved in vasculogenesis and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035789 and metanephric mesenchymal cell migration and biological process this GO :0035791 and platelet-derived growth factor receptor-beta signaling pathway and biological process this GO :0035793 and positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway and biological process this GO :0035909 and aorta morphogenesis and biological process this GO :0036120 and cellular response to platelet-derived growth factor stimulus and biological process this GO :0038085 and vascular endothelial growth factor binding and molecular function this GO :0038091 and positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042060 and wound healing and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043202 and lysosomal lumen and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043548 and phosphatidylinositol 3-kinase binding and molecular function this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0043627 and response to estrogen and biological process this GO :0045087 and innate immune response and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0046488 and phosphatidylinositol metabolic process and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048008 and platelet-derived growth factor receptor signaling pathway and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048407 and platelet-derived growth factor binding and molecular function this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0048705 and skeletal system morphogenesis and biological process this GO :0048745 and smooth muscle tissue development and biological process this GO :0048839 and inner ear development and biological process this GO :0050730 and regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050921 and positive regulation of chemotaxis and biological process this GO :0055003 and cardiac myofibril assembly and biological process this GO :0055093 and response to hyperoxia and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0060981 and cell migration involved in coronary angiogenesis and biological process this GO :0061298 and retina vasculature development in camera-type eye and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071670 and smooth muscle cell chemotaxis and biological process this GO :0072075 and metanephric mesenchyme development and biological process this GO :0072262 and metanephric glomerular mesangial cell proliferation involved in metanephros development and biological process this GO :0072275 and metanephric glomerulus morphogenesis and biological process this GO :0072277 and metanephric glomerular capillary formation and biological process this GO :0072278 and metanephric comma-shaped body morphogenesis and biological process this GO :0072284 and metanephric S-shaped body morphogenesis and biological process this GO :0090280 and positive regulation of calcium ion import and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process this GO :2000573 and positive regulation of DNA biosynthetic process and biological process, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0023019 and signal transduction involved in regulation of gene expression and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030324 and lung development and biological process this GO :0030325 and adrenal gland development and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030539 and male genitalia development and biological process this GO :0031226 and intrinsic component of plasma membrane and cellular component this GO :0033327 and Leydig cell differentiation and biological process this GO :0035790 and platelet-derived growth factor receptor-alpha signaling pathway and biological process this GO :0038085 and vascular endothelial growth factor binding and molecular function this GO :0038091 and positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042060 and wound healing and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048008 and platelet-derived growth factor receptor signaling pathway and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048407 and platelet-derived growth factor binding and molecular function this GO :0048557 and embryonic digestive tract morphogenesis and biological process this GO :0048701 and embryonic cranial skeleton morphogenesis and biological process this GO :0048704 and embryonic skeletal system morphogenesis and biological process this GO :0048705 and skeletal system morphogenesis and biological process this GO :0050920 and regulation of chemotaxis and biological process this GO :0055003 and cardiac myofibril assembly and biological process this GO :0060021 and palate development and biological process this GO :0060325 and face morphogenesis and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0061298 and retina vasculature development in camera-type eye and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070527 and platelet aggregation and biological process this GO :0071230 and cellular response to amino acid stimulus and biological process this GO :0072277 and metanephric glomerular capillary formation and biological process this GO :2000249 and regulation of actin cytoskeleton reorganization and biological process this GO :2000739 and regulation of mesenchymal stem cell differentiation and biological process, 74208 and IDBG-646273 and ENSBTAG00000002804 and 527165, platelet-derived growth factor receptor |
| Identity | 8804 |
| Gene | PDGFRB |
| Long gene name | platelet derived growth factor receptor beta |
| Synonyms gene | PDGFR |
| Synonyms gene name | beta polypeptide , platelet-derived growth factor receptor |
| Locus | 5q32 |
| Discovery year | 2001-06-22 |
| GenBank acession | M21616 |
| Entrez gene record | 5159 |
| RefSeq identity | NM_002609 |
| Classification | I-set domain containing CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT | OTTHUMG00000130053 |
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