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PDI Antibody

PDI Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePDI Primary Polyclonal Antibody
Also known asPDI PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPDI
SpecificityThis is a highly specific antibody against PDI
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDI
Gene ID number2923
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen PDI, Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively), The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER, This retention is reported to be mediated by a KDEL receptor, as well as the reduction of disulphide bonds in proteins, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds, which catalyses disulphide interchange between thiols and protein dilsulphides, The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ERBA2L, ERp57, ERp60, ERp61, Erp, Grp58, P4HB, PDI, PDI-Q2, PDIA1, PDIA1_HUMAN, PDIP, PI-PLC, PLC[a], PO4DB, Pancreatic protein disulfide isomerase, Pdia3, Plca, Protein disulfide isomerase, Protein disulfide isomerase A2, Protein disulfide isomerase family A member 2, Protein Disulfide lsomerase
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPDI
Short namePDI Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePDI (Antibody to)
Alternative techniqueantibodies
Identity 18367
Gene PADI1
Long gene name peptidyl arginine deiminase 1
Synonyms gene name peptidyl arginine deiminase, type I
Synonyms HPAD10 PDI1 PDI PAD1
Synonyms name peptidylarginine deiminase type I protein-arginine deiminase type-1 hPAD-colony 10
Locus 1p36, 13
Discovery year 2002-03-12
GenBank acession AB033768
Entrez gene record 29943
Pubmed identfication 12416996
RefSeq identity NM_013358
Classification Peptidyl arginine deiminases
Havana BLAST/BLAT OTTHUMG00000002294

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