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PDIA1 (1530CT836.11.53) Monoclonal Antibody

PDIA1 (1530CT836.11.53) Monoclonal Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name11, 53) Monoclonal Antibody, PDIA1 (1530CT836
Also known as11, 53) Monoclonal Antibody, PDIA1 (1530CT836
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPDIA1
SpecificityThis is a highly specific antibody against PDIA1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number11, 1530CT836, 53
SourceThis PDIA1 antibody is generated from a mouse immunized with a recombinant protein of human PDIA1
Gene ID number5034
Swiss ProtP07237
Tested ApplicationsWB
Recommended dilutionsWB(1:4000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP, At high concentrations, At low concentrations, At the cell surface, Inside the cell, May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis, May therefore cause structural modifications of exofacial proteins, Receptor for LGALS9, altering the plasma membrane redox state and enhancing cell migration (PubMed:21670307), breakage and rearrangement of disulfide bonds, facilitates aggregation (anti-chaperone activity), functions as a chaperone that inhibits aggregation of misfolded proteins, increasing disulfide reductase activity at the plasma membrane, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell, seems to form/rearrange disulfide bonds of nascent proteins, the interaction retains P4HB at the cell surface of Th2 T helper cells, This multifunctional protein catalyzes the formation
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CLCRP1, Cellular thyroid hormone-binding protein, ERBA2L, GIT, P4HB, P4Hbeta, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB, Prolyl 4-hydroxylase subunit beta, Protein disulfide-isomerase, p55, DSI
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target11, 53) Monoclonal, PDIA1 (1530CT836
Short name11, 53) Monoclonal Antibody, PDIA1 (1530CT836
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name11, 53) monoclonal (Antibody to), PDIA1 (1530CT836
Alternative techniqueantibodies
Identity 8548
Gene P4HB
Long gene name prolyl 4-hydroxylase subunit beta
Synonyms gene PO4DB ERBA2L
Synonyms gene name 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide , beta polypeptide (protein disulfide isomerase, beta polypeptide (protein disulfide isomerase-associated 1) procollagen-proline, beta polypeptide prolyl 4-hydroxylase, procollagen-proline, thyroid hormone binding protein p55) procollagen-proline
Synonyms PDIA1 PROHB DSI GIT PDI PO4HB P4Hbeta
Synonyms name member 1 collagen prolyl 4-hydroxylase beta , protein disulfide isomerase-associated 1 protein disulfide isomerase family A
Locus 17q25, 3
Discovery year 1986-01-01
GenBank acession J02783
Entrez gene record 5034
Pubmed identfication 8111381
RefSeq identity NM_000918
Classification Protein disulfide isomerases
Havana BLAST/BLAT OTTHUMG00000150269

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