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PDIA2 Antibody

PDIA2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePDIA2 Primary Polyclonal Antibody
Also known asPDIA2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPDIA2
SpecificityThis is a highly specific antibody against PDIA2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDIA2
Gene ID number64714
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen PDI, Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively), The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER, This retention is reported to be mediated by a KDEL receptor, as well as the reduction of disulphide bonds in proteins, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds, which catalyses disulphide interchange between thiols and protein dilsulphides, The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names PDA2, PDI, PDIA2, PDIA2_HUMAN, PDIP, Protein disulfide isomerase, Protein disulfide isomerase A2, Protein disulfide isomerase family A member 2, Pancreatic protein disulfide isomerase
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPDIA2
Short namePDIA2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name member 2 (Antibody to), protein disulfide isomerase family A
Alternative techniqueantibodies
Alternative to gene target BT, PDIA2 and IDBG-7384 and ENSG00000185615 and 64714, Pdia2 and IDBG-154856 and ENSMUSG00000024184 and 69191, member 2, multiple, peptidyl-proline 4-dioxygenase activity, this GO :0003756 and protein disulfide isomerase activity and molecular function this GO :0005496 and steroid binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0006457 and protein folding and biological process this GO :0006621 and protein retention in ER lumen and biological process this GO :0008152 and metabolic process and biological process this GO :0016209 and antioxidant activity and molecular function this GO :0016491 and oxidoreductase activity and molecular function this GO :0016853 and isomerase activity and molecular function this GO :0019511 and peptidyl-proline hydroxylation and biological process this GO :0031545 and peptidyl-proline 4-dioxygenase activity and molecular function this GO :0034976 and response to endoplasmic reticulum stress and biological process this GO :0045454 and cell redox homeostasis and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :1902175 and regulation of oxidative stress-induced intrinsic apoptotic signaling pathway and biological process, this GO :0003756: protein disulfide isomerase activity, this GO :0003756: protein disulfide isomerase activity and also this GO :0005496: steroid binding and also this GO :0005515: protein binding and also this GO :0016209: antioxidant activity and also this GO :0016491: oxidoreductase activity and also this GO :0016853: isomerase activity and also this GO :0031545: peptidyl-proline 4-dioxygenase activity, this GO :0005496: steroid binding, this GO :0005515: protein binding, this GO :0016209: antioxidant activity, this GO :0016491: oxidoreductase activity, this GO :0016853: isomerase activity, this GO :0031545: peptidyl-proline 4-dioxygenase activity, 51496 and IDBG-633666 and ENSBTAG00000016575 and 504356, protein disulfide isomerase family A
Identity 14180
Gene PDIA2
Long gene name protein disulfide isomerase family A member 2
Synonyms gene PDIP
Synonyms gene name member 2 , pancreatic protein disulfide isomerase-associated 2 protein disulfide isomerase family A, protein disulfide isomerase
Synonyms PDA2 PDI PDIR
Locus 16p13, 3
Discovery year 2000-12-21
GenBank acession U19948
Entrez gene record 64714
Pubmed identfication 8561901
RefSeq identity NM_006849
Classification Protein disulfide isomerases
Havana BLAST/BLAT OTTHUMG00000064891

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