PDPK1(Ser393) Antibody, Biotin Conjugated

PDPK1(Ser393) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 350

Size 0.1ml

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Long name	Biotin Conjugated, PDPK1(Ser393) Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	PDPK1 Ser393
Specificity	This is a highly specific antibody against PDPK1 Ser393
Modification	Phosphorylation
Modification site	Ser393
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic phosphopeptide derived from human PDPK1 around the phosphorylation site of Ser393
Gene ID number	5170
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research, PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop, PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3, There are three named isoforms, eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis, 4, 5-trisphosphate, PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	PDK1
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	PDPK1(Ser393) Conjugated
Short name	Conjugated, PDPK1(Ser393) Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, PDPK1(Ser393) (Antibody to)
Alternative technique	antibodies
Identity	8816
Gene	PDPK1
Long gene name	3-phosphoinositide dependent protein kinase 1
Synonyms name	PkB kinase
Locus	16p13, 3
Discovery year	1998-03-23
GenBank acession	AF017995
Entrez gene record	5170
Pubmed identfication	9094314 9445477
Havana BLAST/BLAT	OTTHUMG00000128874

PDPK1(Ser393) Antibody, Biotin Conjugated

PDPK1(Ser393) Antibody, Biotin Conjugated size: 0.1ml 350

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