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PDPK1(Ser393) Antibody, Cy3 Conjugated

PDPK1(Ser393) Antibody, Cy3 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, PDPK1(Ser393) Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPDPK1 Ser393
SpecificityThis is a highly specific antibody against PDPK1 Ser393
ModificationPhosphorylation
Modification siteSer393
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PDPK1 around the phosphorylation site of Ser393
Gene ID number5170
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research, PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop, PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3, There are three named isoforms, eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis, 4, 5-trisphosphate, PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms PDK1
Properties 1 of the PDPK1(Ser393) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPDPK1(Ser393) Conjugated
Short name Conjugated, PDPK1(Ser393) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, PDPK1(Ser393) (Antibody to)
Alternative techniqueantibodies
Identity 8816
Gene PDPK1
Long gene name 3-phosphoinositide dependent protein kinase 1
Synonyms name PkB kinase
Locus 16p13, 3
Discovery year 1998-03-23
GenBank acession AF017995
Entrez gene record 5170
Pubmed identfication 9094314 9445477
Havana BLAST/BLAT OTTHUMG00000128874

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