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PDPK1(Ser396) Antibody

PDPK1(Ser396) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePDPK1(Ser396) Primary Polyclonal Antibody
Also known asPDPK1(Ser396) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPDPK1 Ser396
SpecificityThis is a highly specific antibody against PDPK1 Ser396
Modification(s)Phosphorylation
Modification site(s)Ser396
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PDK1 around the phosphorylation site of Ser396
Gene ID number5170
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research, PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop, PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3, There are three named isoforms, eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis, 4, 5-trisphosphate, PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 3 phosphoinositide dependent protein kinase 1, MGC20087 MGC35290, PDK 1, PDPK 1, PDPK1, PDPK1_HUMAN, PRO0461, PkB kinase, PkB kinase like gene 1, PkB like, PkB like 1, hPDK 1, hPDK1, PDPK1phospho S396
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPDPK1(Ser396)
Short namePDPK1(Ser396) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePDPK1(Ser396) (Antibody to)
Alternative techniqueantibodies
Identity 8816
Gene PDPK1
Long gene name 3-phosphoinositide dependent protein kinase 1
Synonyms PDK1
Synonyms name PkB kinase
Locus 16p13, 3
Discovery year 1998-03-23
GenBank acession AF017995
Entrez gene record 5170
Pubmed identfication 9094314 9445477
Havana BLAST/BLAT OTTHUMG00000128874

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