Name : PDPK1(Ser396) Antibody, HRP Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN5045555156
| Long name | HRP Conjugated, PDPK1(Ser396) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | HRP Conjugated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PDPK1 Ser396 |
| Specificity | This is a highly specific antibody against PDPK1 Ser396 |
| Modification | Phosphorylation |
| Modification site | Ser396 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PDK1 around the phosphorylation site of Ser396 |
| Gene ID number | 5170 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research, PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop, PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3, There are three named isoforms, eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis, 4, 5-trisphosphate, PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | PDK1 |
| Properties | Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase  |
| Gene target | PDPK1(Ser396) Conjugated |
| Short name | Conjugated, PDPK1(Ser396) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | HRP |
| Alternative name | horseradish peroxidase coupled, PDPK1(Ser396) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 8816 |
| Gene | PDPK1 |
| Long gene name | 3-phosphoinositide dependent protein kinase 1 |
| Synonyms name | PkB kinase |
| Locus | 16p13, 3 |
| Discovery year | 1998-03-23 |
| GenBank acession | AF017995 |
| Entrez gene record | 5170 |
| Pubmed identfication | 9094314 9445477 |
| Havana BLAST/BLAT | OTTHUMG00000128874 |