Name : PDPK1(Ser410) Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN6795153480
| Long name | ALEXA FLUOR 555 Conjugated, PDPK1(Ser410) Polyclonal Antibody |
| Also known as | Anti-PDPK1 Ser410 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PDPK1 Ser410 |
| Specificity | This is a highly specific antibody against PDPK1 Ser410 |
| Modification | Phosphorylation |
| Modification Site | Ser410 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PDPK1 around the phosphorylation site of Ser410 |
| Gene ID Number | 5170 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research, PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop, PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3, There are three named isoforms, eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis, 4, 5-trisphosphate, PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | PDK1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | PDPK1(Ser410) |
| Short name | PDPK1(Ser410) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, PDPK1(Ser410) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 8816 |
| Gene | PDPK1 |
| Long gene name | 3-phosphoinositide dependent protein kinase 1 |
| Synonyms name | PkB kinase |
| Locus | 16p13, 3 |
| Discovery year | 1998-03-23 |
| GenBank acession | AF017995 |
| Entrez gene record | 5170 |
| Pubmed identfication | 9094314 9445477 |
| Havana BLAST/BLAT | OTTHUMG00000128874 |