Name : PDPK1(Ser410) Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN1722475325
| Long name | ALEXA FLUOR 647 Conjugated, PDPK1(Ser410) Polyclonal Antibody |
| Also known as | Anti-PDPK1 Ser410 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PDPK1 Ser410 |
| Specificity | This is a highly specific antibody against PDPK1 Ser410 |
| Modification | Phosphorylation |
| Modification Site | Ser410 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PDPK1 around the phosphorylation site of Ser410 |
| Gene ID Number | 5170 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research, PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop, PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3, There are three named isoforms, eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis, 4, 5-trisphosphate, PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | PDK1 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the PDPK1(Ser410) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | PDPK1(Ser410) |
| Short name | PDPK1(Ser410) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, PDPK1(Ser410) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 8816 |
| Gene | PDPK1 |
| Long gene name | 3-phosphoinositide dependent protein kinase 1 |
| Synonyms name | PkB kinase |
| Locus | 16p13, 3 |
| Discovery year | 1998-03-23 |
| GenBank acession | AF017995 |
| Entrez gene record | 5170 |
| Pubmed identfication | 9094314 9445477 |
| Havana BLAST/BLAT | OTTHUMG00000128874 |