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PEA3 Antibody

PEA3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePEA3 Primary Polyclonal Antibody
Also known asPEA3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPEA3
SpecificityThis is a highly specific antibody against PEA3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PEA3
Gene ID number2118
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Drosophila E74, Each of these proteins recognizes similar motifs in DNA that share a centrally located 5'-GGAA-3' element, Ets-2 and Fli-1, For instance, It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core, PEA3 binds the motif 5'-AGGAAG-3' (the PEA-3 motif), PEA3 is expressed at readily detectable levels in cells of epithelial and fibroblastic origin but is not expressed in hematopoietic cells, These include mouse PU, This is in contrast to other members of the Ets gene family, although PU, but does not bind to the sequence 5'-AGGAAC-3', chicken and human Ets-2 and rat GABP-a, each of which is expressed primarily in cells of hematopoietic origin, mouse and human Ets-1, recognized by PU, such as Ets-1, 1, 1, 1 binds equally well to both sequences, Several members of the Ets gene family are known to encode sequence-specific DNA binding proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names E1A-F, E1AF, ETV4, PEA3, PEAS3, ets, ets variant 4, polymoma virus enhancer 3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPEA3
Short namePEA3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePEA3 (Antibody to)
Alternative techniqueantibodies
Identity 3493
Gene ETV4
Long gene name ETS variant 4
Synonyms gene name E1AF) , ets variant gene 4 (E1A enhancer-binding protein
Synonyms E1A-F E1AF PEA3
Synonyms name E1A enhancer binding protein
Locus 17q21, 31
Discovery year 1995-03-27
GenBank acession U18018
Entrez gene record 2118
Pubmed identfication 8530053 1547944
RefSeq identity NM_001986
Classification ETS transcription factor family
Havana BLAST/BLAT OTTHUMG00000180884

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