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PERK(Thr980) Antibody, Biotin Conjugated

PERK(Thr980) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, PERK(Thr980) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPERK Thr980
SpecificityThis is a highly specific antibody against PERK Thr980
ModificationPhosphorylation
Modification siteThr980
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range960-1010/1114
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from mouse PERK around the phosphorylation site of Thr981
Gene ID number13666
Swiss ProtQ9Z2B5
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Involved in control of mitochondrial morphology and function, Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis, Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms PEK PERK
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPERK(Thr980) Conjugated
Short name Conjugated, PERK(Thr980) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, PERK(Thr980) (Antibody to)
Alternative techniqueantibodies
Identity 3255
Gene EIF2AK3
Long gene name eukaryotic translation initiation factor 2 alpha kinase 3
Locus 2p11, 2
Discovery year 1999-06-14
GenBank acession AF110146
Entrez gene record 9451
Pubmed identfication 10026192 10575235
RefSeq identity NM_004836
Havana BLAST/BLAT OTTHUMG00000155046
Locus Specific Databases LRG_1024

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