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Peroxiredoxin 1 Antibody

Peroxiredoxin 1 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPeroxiredoxin 1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the Peroxiredoxin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis Peroxiredoxin 1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q06830
PurityAntigen affinity
Description An intramolecular disulfide bond between the GDE2 N- and C-terminal domains inhibits GDE2 function, Immunoprecipitation analysis showed that GDE2 interacted directly with PRDX1 in embryonic chicken spinal cord extracts and in transfected HEK293T cells, In differentiating spinal cord, PAGA or NKEFA, PRDX1 was expressed in differentiating motor neuron cells in developing embryonic chicken and mouse spinal cords, Prdx1 was required to activate Gde2 by reducing an intramolecular cystine bridge between the Gde2 N- and C-terminal domains, The PRDX1 gene is mapped on 1p34, This gene encodes a member of a family of antioxidant enzymes, This protein may have a proliferative effect and play a role in cancer development or progression, also called PRX1, and that reduction of this cystine by PRDX1 activates GDE2 for the induction of motor neuron differentiation, is a thiol reductase that plays critical roles in oxidative and thermal stress defense mechanisms through its abilities to metabolize H2O2 and act as a molecular chaperone, respectively, which reduce hydrogen peroxide and alkyl hydroperoxides, 1, Peroxiredoxin 1
ImmunogenAn amino acid sequence from the C-terminus of human PRDX1 (KPDVQKSKEYFSKQK) was used as the immunogen for this Peroxiredoxin 1 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Peroxiredoxin 1 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPeroxiredoxin 1
Short namePeroxiredoxin 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePeroxiredoxin 1 (Antibody to)
Alternative techniqueantibodies
Identity 9352
Gene PRDX1
Long gene name peroxiredoxin 1
Synonyms gene PAGA
Synonyms NKEFA
Locus 1p34, 1
Discovery year 1993-11-01
GenBank acession BC021683
Entrez gene record 5052
Pubmed identfication 8496166
RefSeq identity NM_181697
Classification Peroxiredoxins
Havana BLAST/BLAT OTTHUMG00000007738

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