Peroxiredoxin 5 Antibody (PRDX5)

Peroxiredoxin 5 Antibody (PRDX5) size: 0.1mg 389

Price 389

Size 0.1mg

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Category	Antibody
Concentration	2ml sterile DI water, 5mg/ml if reconstituted with 0
Form	Antigen affinity purified
Conjugation	Unconjugated
Clone	Polyclonal antibody
Recognised antigen	Peroxiredoxin 5 (PRDX5)
Host animal	Rabbit (Oryctolagus cuniculus)
Clonality	Polyclonal (rabbit origin)
Species reactivity	Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications	IHC-P, WB
Recommended dilutions	5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes	Titration of the Peroxiredoxin 5 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented use	This Peroxiredoxin 5 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #	P30044
Purity	Antigen affinity
Description	Functional analysis showed that Peroxiredoxin 5 has antioxidant activity equivalent to that of CAT, Northern blot analysis revealed ubiquitous expression of a 1, PRDX5 displays mitochondrial presequence features and has 3 cysteines implicated in antioxidant activity and a C-terminal SQL peroxisomal targeting sequence, Peroxiredoxin 5 plays a protective role against oxidative stress in human cartilage, While PRDX5 was localized to fibroblasts in normal tendon, also known as PRX5 and PRDX5, and the increase in PRDX5 expression correlated with reduced peroxide levels, is a member of the peroxiredoxin family and may play an antioxidant protective role in various tissues under nonpathologic conditions and during inflammatory processes, it was localized to fibroblasts and endothelial cells in degenerative tendon, mRNA and protein levels increased at 12 hours, 0-kb PRDX5 transcript in tissues and cell lines, Peroxiredoxin 5
Immunogen	mouse and rat), An amino acid sequence from the C-terminus of human PRDX5 (DDSLVSIFGNRRLKRF) was used as the immunogen for this Peroxiredoxin 5 antibody (100% homologous in human
Storage	Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Peroxiredoxin 5 antibody can be stored for up to one month at 4oC, After reconstitution
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target	Peroxiredoxin 5 (PRDX5)
Short name	Peroxiredoxin 5 Antibody (PRDX5)
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	Peroxiredoxin 5 (Antibody to) (peroxiredoxin 5)
Alternative technique	antibodies
Alternative to gene target	ACR1 and AOEB166 and B166 and HEL-S-55 and PLP and PMP20 and PRDX6 and prx-V and PRXV, PRDX5 and IDBG-53649 and ENSG00000126432 and 25824, PRDX5 and IDBG-643929 and ENSBTAG00000008648 and 282885, Prdx5 and IDBG-136962 and ENSMUSG00000024953 and 54683, nuclei, peroxynitrite reductase activity, this GO :0001016 and RNA polymerase III regulatory region DNA binding and molecular function this GO :0004601 and peroxidase activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005782 and peroxisomal matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0016209 and antioxidant activity and molecular function this GO :0016480 and negative regulation of transcription from RNA polymerase III promoter and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0034614 and cellular response to reactive oxygen species and biological process this GO :0042744 and hydrogen peroxide catabolic process and biological process this GO :0043027 and cysteine-type endopeptidase inhibitor activity involved in apoptotic process and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0046983 and protein dimerization activity and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051354 and negative regulation of oxidoreductase activity and biological process this GO :0051920 and peroxiredoxin activity and molecular function this GO :0055114 and oxidation-reduction process and biological process this GO :0060785 and regulation of apoptosis involved in tissue homeostasis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070995 and NADPH oxidation and biological process this GO :0072541 and peroxynitrite reductase activity and molecular function this GO :2001057 and reactive nitrogen species metabolic process and biological process this GO :2001141 and regulation of RNA biosynthetic process and biological process, this GO :0001016: RNA polymerase III regulatory region DNA binding, this GO :0001016: RNA polymerase III regulatory region DNA binding and also this GO :0004601: peroxidase activity and also this GO :0005102: receptor binding and also this GO :0016209: antioxidant activity and also this GO :0016491: oxidoreductase activity and also this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process and also this GO :0046983: protein dimerization activity and also this GO :0051920: peroxiredoxin activity and also this GO :0072541: peroxynitrite reductase activity, this GO :0004601: peroxidase activity, this GO :0005102: receptor binding, this GO :0016209: antioxidant activity, this GO :0016491: oxidoreductase activity, this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, this GO :0046983: protein dimerization activity, this GO :0051920: peroxiredoxin activity, this GO :0072541: peroxynitrite reductase activity, peroxiredoxin 5
Identity	9355
Gene	PRDX5
Long gene name	peroxiredoxin 5
Synonyms	ACR1 AOEB166 MGC142285 PRXV PMP20 B166 PRDX6 PLP SBBI10 MGC117264 MGC142283
Synonyms name	antioxidant enzyme B166 thioredoxin peroxidase PMP20 peroxisomal antioxidant enzyme TPx type VI liver tissue 2D-page spot 71B Alu co-repressor 1
Locus	11q13, 1
Discovery year	2000-07-31
GenBank acession	AF197952
Entrez gene record	25824
Pubmed identfication	10514471 10521424
RefSeq identity	NM_181651
Classification	Peroxiredoxins
Havana BLAST/BLAT	OTTHUMG00000168805

Peroxiredoxin 5 Antibody (PRDX5)

Peroxiredoxin 5 Antibody (PRDX5) size: 0.1mg 389

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