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PFK2 (Ser467) Antibody, Biotin Conjugated

PFK2 (Ser467) Antibody, Biotin Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Biotin Conjugated, PFK2 (Ser467) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPFK2 Ser467
Specificity This phosphorylated site is homologous to that of Ser467 in Mouse and Ser496 in Rat, This is a highly specific antibody against PFK2 Ser467
ModificationPhosphorylation
Modification siteSer467
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range458-520/520
Subcellular locationNucleus
SourceKLH conjugated synthetic phosphopeptide derived from human PFK2 around the phosphorylation site of Ser467
Gene ID number5209
Swiss ProtQ16875
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Fructose-2, Glycolytic flux is key to tumour growth, Several lines of evidence suggest that 6 Phosphofructo 2 Kinase is also involved in obesity, and small molecule inhibition of 6 Phosphofructo 2 Kinase suppresses both glycolytic flux and tumour growth, which catalyses a key step in the glycoytic pathway, 6 Phosphofructo 2 Kinase plays a role in the synthesis and degradation of fructose 2, 6-bisphosphate, 6-bisphosphate acts as an allosteric regulator of 6-phosphofructo-1-kinase (PFK1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms 6-phosphofructo-2-kinase/fructose-2, 6PF-2-K/Fru-2, 6PF-2-K/Fru-2, IPFK2, PFK/FBPase 3, PFKFB3, Renal carcinoma antigen NY-REN-56, iPFK-2, 6-P2ase 3, 6-P2ase brain/placenta-type isozyme, 6-bisphosphatase 3, PFK2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPFK2 (Ser467) Conjugated
Short name Conjugated, PFK2 (Ser467) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, PFK2 (Ser467) (Antibody to)
Alternative techniqueantibodies

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