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PFKL (Ser775) Antibody

PFKL (Ser775) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePFKL (Ser775) Primary Polyclonal Antibody
Also known asPFKL (Ser775) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPFKL Ser775
SpecificityThis is a highly specific antibody against PFKL Ser775
Modification(s)Phosphorylation
Modification site(s)Ser775
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PFKL around the phosphorylation site of Ser775
Gene ID number5211
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Mammalian PFK is a tetramer made up of diverse combinations of three isoenzymes: muscle (PFK-1), Overexpression of PFKL in transgenic mice results in a diminished glucose-induced insulin response, PFKL (phosphofructokinase, PFKL is expressed at high levels in Down's syndrome (DS) patients, also referred to as PFK-B (Phosphofructo-1-kinase isozyme B), liver (PFKL) and platelet (PFKP), liver), phosphofructokinase 1 or phosphohexokinase, predominates in organs with active gluconeogenesis, such as liver and kidney, suggesting a possible role for PFKL in the pathogenesis of DS, which suggests that PFKL may play a role in glucose-induced insulin secretion, 6-bisphosphate, Phosphofructokinases (PFKs) are regulatory glycolytic enzymes that catalyze the irreversible conversion of fructose-6-phosphate to fructose-1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 6-phosphofructokinase, Fructose 6 Phosphate Kinase 6 Phosphofructokinase Muscle Type, GSD7, K6PF_HUMAN, PFK-A, PFKA, PFKL, PFKL phospho Ser775, PFKM, PFKP, PFKX, Phosphofructo 1 Kinase Isozyme A, Phosphofructo-1-kinase isozyme A, Phosphofructokinase, Phosphofructokinase, Phosphofructokinase, Phosphofructokinase 1, Phosphofructokinase M, Phosphofructokinase-M, Phosphohexokinase, muscle, muscle type, muscle type, p-PFKL Ser775, polypeptide X, PFKL phospho S775
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPFKL (Ser775)
Short namePFKL (Ser775) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePFKL (Ser775) (Antibody to)
Alternative techniqueantibodies
Identity 8876
Gene PFKL
Long gene name liver type , phosphofructokinase
Locus 21q22, 3
Discovery year 1986-01-01
Entrez gene record 5211
Havana BLAST/BLAT OTTHUMG00000086910

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