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PFKL (Ser775) Antibody, Biotin Conjugated

PFKL (Ser775) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, PFKL (Ser775) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPFKL Ser775
SpecificityThis is a highly specific antibody against PFKL Ser775
ModificationPhosphorylation
Modification siteSer775
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PFKL around the phosphorylation site of Ser775
Gene ID number5211
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Mammalian PFK is a tetramer made up of diverse combinations of three isoenzymes: muscle (PFK-1), Overexpression of PFKL in transgenic mice results in a diminished glucose-induced insulin response, PFKL (phosphofructokinase, PFKL is expressed at high levels in Down's syndrome (DS) patients, also referred to as PFK-B (Phosphofructo-1-kinase isozyme B), liver (PFKL) and platelet (PFKP), liver), phosphofructokinase 1 or phosphohexokinase, predominates in organs with active gluconeogenesis, such as liver and kidney, suggesting a possible role for PFKL in the pathogenesis of DS, which suggests that PFKL may play a role in glucose-induced insulin secretion, 6-bisphosphate, Phosphofructokinases (PFKs) are regulatory glycolytic enzymes that catalyze the irreversible conversion of fructose-6-phosphate to fructose-1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPFKL (Ser775) Conjugated
Short name Conjugated, PFKL (Ser775) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, PFKL (Ser775) (Antibody to)
Alternative techniqueantibodies
Identity 8876
Gene PFKL
Long gene name liver type , phosphofructokinase
Locus 21q22, 3
Discovery year 1986-01-01
Entrez gene record 5211
Havana BLAST/BLAT OTTHUMG00000086910

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