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PHGDH Antibody

PHGDH Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePHGDH Primary Polyclonal Antibody
Also known asPHGDH PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPHGDH
SpecificityThis is a highly specific antibody against PHGDH
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range120-160/533
Subcellular locationIntracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PHGDH
Gene ID number26227
Swiss ProtO43175
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 3PGDH is regulated at the transcriptional level depending on tissue specificity and cellular proliferative status (2), 3PGDH protein is 544 amino acids in length, 3PGDH protein is also highly expressed in adult and fetal brain tissues (3), 3PGDH protein plays an important role in the metabolism, The trophic actions of glial cells on Purkinje neurons are mediated by L-serine and glycine, Two distinct mRNA transcripts that encode for 3PGDH protein in normal human tissues are dominant 2, and 710 bp mRNA, and function of the central nervous system (3) and its deficiency is a treatable congential error (4-5) that impairs L-serine biosynthesis which is characterized by congenital microcephaly, and heart, and pancreas, and seizures (3), and weakly expressed in thymus, brain, colon, development, kidney, liver, ovary, psychomotor retardation, testis, which are glia-derived trophic factors synthesized by 3PGDH (1), which is highly expressed in heart and skeletal muscle (2), which is highly expressed in prostate, 1 kb mRNA, The survival and development of central neurons require the supply of trophic factors by glial cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 3-PGDH, 3PGDH, D-3-phosphoglycerate dehydrogenase, HEL-S-113, NLS1, PDG, PGAD, PGD, PGDH, PGDH3, PHGDH, PHGDHD, SERA, NLS
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPHGDH
Short namePHGDH Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePHGDH (Antibody to)
Alternative techniqueantibodies
Identity 8923
Gene PHGDH
Long gene name phosphoglycerate dehydrogenase
Synonyms SERA PGDH PDG
Locus 1p12
Discovery year 1999-11-22
GenBank acession BC011262
Entrez gene record 26227
RefSeq identity NM_006623
Havana BLAST/BLAT OTTHUMG00000012100

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