Filters

PHGDH Antibody, FITC Conjugated

PHGDH Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, PHGDH Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPHGDH
SpecificityThis is a highly specific antibody against PHGDH
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range120-160/533
Subcellular locationIntracellular
SourceKLH conjugated synthetic peptide derived from human PHGDH
Gene ID number26227
Swiss ProtO43175
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 3PGDH is regulated at the transcriptional level depending on tissue specificity and cellular proliferative status (2), 3PGDH protein is 544 amino acids in length, 3PGDH protein is also highly expressed in adult and fetal brain tissues (3), 3PGDH protein plays an important role in the metabolism, The trophic actions of glial cells on Purkinje neurons are mediated by L-serine and glycine, Two distinct mRNA transcripts that encode for 3PGDH protein in normal human tissues are dominant 2, and 710 bp mRNA, and function of the central nervous system (3) and its deficiency is a treatable congential error (4-5) that impairs L-serine biosynthesis which is characterized by congenital microcephaly, and heart, and pancreas, and seizures (3), and weakly expressed in thymus, brain, colon, development, kidney, liver, ovary, psychomotor retardation, testis, which are glia-derived trophic factors synthesized by 3PGDH (1), which is highly expressed in heart and skeletal muscle (2), which is highly expressed in prostate, 1 kb mRNA, The survival and development of central neurons require the supply of trophic factors by glial cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms SERA PGDH PDG
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPHGDH Conjugated
Short name FITC Conjugated, PHGDH Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PHGDH (Antibody to)
Alternative techniqueantibodies
Identity 8923
Gene PHGDH
Long gene name phosphoglycerate dehydrogenase
Locus 1p12
Discovery year 1999-11-22
GenBank acession BC011262
Entrez gene record 26227
RefSeq identity NM_006623
Havana BLAST/BLAT OTTHUMG00000012100

Subscribe to our Newsletter