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Phospho-AKT Antibody (pY326)

Phospho-AKT Antibody (pY326) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPhospho-AKT (pY326)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the phospho-AKT antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis phospho-AKT antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P31749
PurityAntigen affinity
Description AKT1 and the related AKT2 are activated by platelet-derived growth factor, In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival, It was shown that the activation occurs through phosphatidylinositol 3-kinase, Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1, which then phosphorylates and inactivates components of the apoptotic machinery, The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts
ImmunogenThis phospho-AKT antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY326 of human AKT
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-AKT antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPhospho-AKT (pY326)
Short namePhospho-AKT Antibody (pY326)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namephosphorilated-AKT (Antibody to) (pY326)
Alternative techniqueantibodies
Identity 391
Gene AKT1
Long gene name AKT serine/threonine kinase 1
Synonyms gene name v-akt murine thymoma viral oncogene homolog 1
Synonyms RAC PKB PRKBA AKT
Locus 14q32, 33
Discovery year 1986-01-01
GenBank acession M63167
Entrez gene record 207
RefSeq identity NM_005163
Classification Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000170795
Locus Specific Databases LRG_721

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