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Phospho-AKT2 Antibody (pS474)

Phospho-AKT2 Antibody (pS474) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPhospho-AKT2 (pS474)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, DB
Recommended dilutionsDot blot: 1:500
NotesTitration of the phospho-AKT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis phospho-AKT2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P31751
PurityAntigen affinity
Description AKT2 is a general protein kinase capable of phophorylating several known proteins, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors, Furthermore, Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers, AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains
ImmunogenThis phospho-AKT2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS474 of human AKT2
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-AKT2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPhospho-AKT2 (pS474)
Short namePhospho-AKT2 Antibody (pS474)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namephosphorilated-v-akt murine thymoma viral oncogene homolog 2 (Antibody to) (pS474)
Alternative techniqueantibodies
Alternative to gene target AKT2 and IDBG-51270 and ENSG00000105221 and 208, AKT2 and IDBG-637808 and ENSBTAG00000001400 and 534923, Akt2 and IDBG-161456 and ENSMUSG00000004056 and 11652, HIHGHH and PKBB and PKBBETA and PRKBB and RAC-BETA, nuclei, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0005978 and glycogen biosynthetic process and biological process this GO :0006006 and glucose metabolic process and biological process this GO :0006417 and regulation of translation and biological process this GO :0006464 and cellular protein modification process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008643 and carbohydrate transport and biological process this GO :0010748 and negative regulation of plasma membrane long-chain fatty acid transport and biological process this GO :0010907 and positive regulation of glucose metabolic process and biological process this GO :0016301 and kinase activity and molecular function this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016301: kinase activity and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016301: kinase activity, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0030334 and regulation of cell migration and biological process this GO :0031340 and positive regulation of vesicle fusion and biological process this GO :0032000 and positive regulation of fatty acid beta-oxidation and biological process this GO :0032287 and peripheral nervous system myelin maintenance and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032859 and activation of Ral GTPase activity and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0045725 and positive regulation of glycogen biosynthetic process and biological process this GO :0046326 and positive regulation of glucose import and biological process this GO :0060644 and mammary gland epithelial cell differentiation and biological process this GO :0061024 and membrane organization and biological process this GO :0065002 and intracellular protein transmembrane transport and biological process this GO :0071156 and regulation of cell cycle arrest and biological process this GO :0072659 and protein localization to plasma membrane and biological process this GO :0090314 and positive regulation of protein targeting to membrane and biological process this GO :2000147 and positive regulation of cell motility and biological process this GO :2001275 and positive regulation of glucose import in response to insulin stimulus and biological process, v-akt murine thymoma viral oncogene homolog 2
Identity 392
Gene AKT2
Long gene name AKT serine/threonine kinase 2
Synonyms gene name v-akt murine thymoma viral oncogene homolog 2
Locus 19q13, 2
Discovery year 1992-11-05
GenBank acession M77198
Entrez gene record 208
Pubmed identfication 1409633
RefSeq identity NM_001626
Classification Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000137375

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