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Phospho-c-Fos Antibody (pT232)

Phospho-c-Fos Antibody (pT232) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPhospho-c-Fos (pT232)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, DB
Recommended dilutionsDot blot: 1:500
NotesTitration of the phospho-c-Fos antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis phospho-c-Fos antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P01100
PurityAntigen affinity
Description FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites, Has a critical function in regulating the development of cells destined to form and maintain the skeleton, In growing cells, In the heterodimer, It is thought to have an important role in signal transduction, On TGF-beta activation, This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum, [UniProt], activates phospholipid synthesis, cell proliferation and differentiation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling, possibly by activating CDS1 and PI4K2A, c-Fos is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor
ImmunogenThis phospho-c-Fos antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT232 of the human protein
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-c-Fos antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPhospho-c-Fos (pT232)
Short namePhospho-c-Fos Antibody (pT232)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namephosphorilated-c-FBJ murine osteosarcoma viral oncogene homolog (Antibody to) (pT232)
Alternative techniqueantibodies

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