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Phospho-CDC25A Antibody (pS293)

Phospho-CDC25A Antibody (pS293) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPhospho-CDC25A (pS293)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the phospho-CDC25A antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis phospho-CDC25A antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P30304
PurityAntigen affinity
Description CDC25A is an oncogene, CDC25A is required for progression from G1 to the S phase of the cell cycle, CDC25A is specifically degraded in response to DNA damage, It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups, Two transcript variants encoding different isoforms have been found for this gene, although its exact role in oncogenesis has not been demonstrated, which prevents cells with chromosomal abnormalities from progressing through cell division, CDC25A is a member of the CDC25 family of phosphatases
ImmunogenThis phospho-CDC25A antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS293 of human CDC25A
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-CDC25A antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPhospho-CDC25A (pS293)
Short namePhospho-CDC25A Antibody (pS293)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namephosphorilated-CDC25A (Antibody to) (pS293)
Alternative techniqueantibodies
Identity 1725
Gene CDC25A
Long gene name cell division cycle 25A
Synonyms gene name cell division cycle 25A cell division cycle 25 homolog A (S, cerevisiae) cell division cycle 25 homolog A (S, pombe)
Locus 3p21, 31
Discovery year 1992-07-31
GenBank acession M81933
Entrez gene record 993
Pubmed identfication 1836978
RefSeq identity NM_001789
Classification Class III Cys-based CDC25 phosphatases
Havana BLAST/BLAT OTTHUMG00000133535

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