Name : Phospho-HER4/ERBB4 Antibody (pY1188)
Supplier : NJS POLY
Price :406
SKU : GEN9443291204
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Phospho-HER4/ERBB4 (pY1188) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IHC, WB |
| Recommended dilutions | IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes | Titration of the phospho-HER4 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This phospho-HER4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q15303 |
| Purity | Antigen affinity |
| Description | ERBB2, It encodes a receptor for NDF/heregulin, and ERBB3, The HER4/ERBB4 gene is a member of the type I receptor tyrosine kinase subfamily that includes EGFR |
| Immunogen | This phospho-HER4 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY1188 of human HER4 |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-HER4 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Phospho-HER4/ERBB4 (pY1188) |
| Short name | Phospho-HER4/ERBB4 Antibody (pY1188) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | phosphorilated-HER4/v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (Antibody to) (pY1188) |
| Alternative technique | antibodies |
| Alternative to gene target | ALS19 and HER4 and p180erbB4, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0007507 and heart development and biological process this GO :0007595 and lactation and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009880 and embryonic pattern specification and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, DNA-templated and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0060045 and positive regulation of cardiac muscle cell proliferation and biological process this GO :0060644 and mammary gland epithelial cell differentiation and biological process this GO :0060749 and mammary gland alveolus development and biological process this GO :0061026 and cardiac muscle tissue regeneration and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :2000366 and positive regulation of STAT protein import into nucleus and biological process, ERBB4 and IDBG-643612 and ENSBTAG00000012647 and, ERBB4 and IDBG-79992 and ENSG00000178568 and 2066, Erbb4 and IDBG-164078 and ENSMUSG00000062209 and 13869, nuclei, this GO :0001755 and neural crest cell migration and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0005154 and epidermal growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0004716: receptor signaling protein tyrosine kinase activity and also this GO :0005154: epidermal growth factor receptor binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0004716: receptor signaling protein tyrosine kinase activity, this GO :0005154: epidermal growth factor receptor binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0042803: protein homodimerization activity, this GO :0044212: transcription regulatory region DNA binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042803: protein homodimerization activity and also this GO :0044212: transcription regulatory region DNA binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0021551 and central nervous system morphogenesis and biological process this GO :0021889 and olfactory bulb interneuron differentiation and biological process this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042523 and positive regulation of tyrosine phosphorylation of Stat5 protein and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043235 and receptor complex and cellular component this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0043653 and mitochondrial fragmentation involved in apoptotic process and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045165 and cell fate commitment and biological process this GO :0045893 and positive regulation of transcription, v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) |
| Identity | 3432 |
| Gene | ERBB4 |
| Long gene name | erb-b2 receptor tyrosine kinase 4 |
| Synonyms gene name | v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 |
| Synonyms | ALS19 HER4 |
| Synonyms name | human epidermal growth factor receptor 4 |
| Locus | 2q34 |
| Discovery year | 1995-09-07 |
| GenBank acession | L07868 |
| Entrez gene record | 2066 |
| Pubmed identfication | 7700649 17018285 |
| RefSeq identity | NM_001042599 |
| Classification | Erb-b2 receptor tyrosine kinases |
| Havana BLAST/BLAT | OTTHUMG00000133012 |