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Phospho-MAP2 Antibody (pS1539)

Phospho-MAP2 Antibody (pS1539) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPhospho-MAP2 (pS1539)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, DB
Recommended dilutionsDot blot: 1:500
NotesTitration of the phospho-MAP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis phospho-MAP2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P11137
PurityAntigen affinity
Description At the same time, Between postnatal days 10 and 20, In the newborn rat brain, It also interacts with neurofilaments, MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats, MAP2 is known to promote microtubule assembly and to form side-arms on microtubules, MAP2a appears, MAP2b and MAP2c are present, There are three forms of MAP2, There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types, This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology, actin, and other elements of the cytoskeleton, the level of MAP2c drops by 10-fold, two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c), while MAP2a is absent, MAP2 is the major microtubule associated protein of brain tissue
ImmunogenThis phospho-MAP2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1539 of human MAP2
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-MAP2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPhospho-MAP2 (pS1539)
Short namePhospho-MAP2 Antibody (pS1539)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namephosphorilated-MAP2 (Antibody to) (pS1539)
Alternative techniqueantibodies
Identity 16672
Gene METAP2
Long gene name methionyl aminopeptidase 2
Synonyms MNPEP p67 MAP2
Synonyms name Peptidase M
Locus 12q22
Discovery year 2001-09-26
GenBank acession U13261
Entrez gene record 10988
Pubmed identfication 7644482 8858118
RefSeq identity NM_006838
Classification Aminopeptidases
Havana BLAST/BLAT OTTHUMG00000170280

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