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phospho Met/C-Met(Tyr1365) Antibody, HRP Conjugated

phospho Met/C-Met(Tyr1365) Antibody, HRP Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name HRP Conjugated, phospho Met/C-Met(Tyr1365) Antibody
CategoryConjugated Primary Antibodies
ConjugationHRP Conjugated
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigenc-Met Tyr1365
SpecificityThis is a highly specific antibody against c-Met Tyr1365
ModificationPhosphorylation
Modification siteTyr1365
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1345-1385/1390
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human C-Met around the phosphorylation site of Tyr1365
Gene ID number4233
Swiss ProtP08581
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as a receptor for Listeria internalin inlB, During embryonic development, Following activation by ligand, GRB2, In adults, Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules, MET signaling plays a role in gastrulation, PI3 kinase-AKT, PLCG1, Promotes also differentiation and proliferation of hematopoietic cells, Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, Regulates many physiological processes including proliferation, SRC, STAT3 or the adapter GAB1, The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects, angiogenesis and kidney formation, development and migration of muscles and neuronal precursors, interacts with the PI3-kinase subunit PIK3R1, mediating entry of the pathogen into cells, morphogenesis and survival, or PLCgamma-PKC, participates in wound healing as well as organ regeneration and tissue remodeling, scattering, Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms AUTS9, HGF receptor, HGF/SF receptor, Hepatocyte growth factor receptor, MET, Proto-oncogene c-Met, RCCP2, SF receptor, Scatter factor receptor, Tyrosine-protein kinase Met, c-Met, HGFR
Properties Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase 
Gene targetphospho Met/C-Met(Tyr1365) Conjugated
Short name Conjugated, phospho Met/C-Met(Tyr1365) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelHRP
Alternative name horseradish peroxidase coupled, phosphorilated Met/C-Met(Tyr1365) (Antibody to)
Alternative techniqueantibodies

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