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Phospho-PDX1 Antibody (pT11)

Phospho-PDX1 Antibody (pT11) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPhospho-PDX1 (pT11)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications DB, ELISA, IF
Recommended dilutionsDot blot: 1:500, Immunofluorescence: 1:100
NotesTitration of the phospho-PDX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis phospho-PDX1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P52945
PurityAntigen affinity
Description Defects in this protein are a cause of pancreatic agenesis, The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression, and glucose transporter type 2, as well as maturity onset diabetes of the young type 4 (MODY4), glucokinase, including insulin, islet amyloid polypeptide, somatostatin, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), PDX1 is a transcriptional activator of several genes
ImmunogenThis phospho-PDX1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT11 of human PDX1
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-PDX1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPhospho-PDX1 (pT11)
Short namePhospho-PDX1 Antibody (pT11)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namephosphorilated-PDX1 (Antibody to) (pT11)
Alternative techniqueantibodies
Identity 21350
Gene PDHX
Long gene name pyruvate dehydrogenase complex component X
Synonyms E3BP proX PDX1 OPDX DLDBP
Locus 11p13
Discovery year 2003-06-24
GenBank acession U82328
Entrez gene record 8050
Pubmed identfication 9467010 12372595
RefSeq identity NM_003477
Havana BLAST/BLAT OTTHUMG00000166491

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