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Phospho-S6K Antibody [p-p70S6K) (pS418)

Phospho-S6K Antibody [p-p70S6K) (pS418) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPhospho-S6K [p-p70S6K) (pS418)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, DB
Recommended dilutionsDot blot: 1:500
NotesTitration of the phospho-S6K antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis phospho-S6K antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P23443
PurityAntigen affinity
Description Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized, Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines, The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation, This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein, p70 S6K is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases
ImmunogenThis phospho-S6K antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS418 of human RPS6KB1
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-S6K antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPhospho-S6K [p-p70S6K) (pS418)
Short namePhospho-S6K Antibody [p-p70S6K) (pS418)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namephosphorilated-S6K (Antibody to) [p-p70S6K) (pS418)
Alternative techniqueantibodies

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