Name : phospholamban Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6489941499
| Long name | phospholamban Primary Polyclonal Antibody |
| Also known as | phospholamban PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | phospholamban |
| Specificity | This is a highly specific antibody against phospholamban |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human phospholamban |
| Gene ID number | 5350 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Believed to assemble into a pentamer, Non-phosphorylated PLB associates with SERCA2a, PKA, PKG, PLB activation occurs when key Serine/Threonine residues in PLB (Ser-10, PLB regulates cardiac contractility and Ca2+ affinity for cardiac SER Ca2+ ATPase (SERCA2a), Phospholamban (PLB), Phosphorylation of PLB causes dissociation from SERCA2a and a subsequent increase in the rate of Ca2+ reuptake into the SER, Ser-16, Thr-17) are phosphorylated by numerous effectors, and CaM kinase, and inhibits Ca2+ reuptake into the SER, is a small, plasma membrane-associated protein found in the SER of cardiac, smooth and slow-twitch muscle, which accelerates ventricular relaxation, which include PKC, The Sarco(endo)plasmic-reticulum (SER) regulatory protein |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CMD1P, PLB, PLN, PPLA_HUMAN, Cardiac phospholamban |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | phospholamban |
| Short name | phospholamban Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | phospholamban (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9080 |
| Gene | PLN |
| Long gene name | phospholamban |
| Synonyms gene | PLB |
| Synonyms | CMD1P |
| Locus | 6q22, 31 |
| Discovery year | 1991-08-22 |
| Entrez gene record | 5350 |
| Pubmed identfication | 1828805 |
| RefSeq identity | NM_002667 |
| Havana BLAST/BLAT | OTTHUMG00000015462 |
| Locus Specific Databases | LRG_390 |