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PHOX2A/CFEOM2 Antibody

PHOX2A/CFEOM2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePHOX2A/CFEOM2 Primary Polyclonal Antibody
Also known asPHOX2A/CFEOM2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPHOX2A/CFEOM2
SpecificityThis is a highly specific antibody against PHOX2A/CFEOM2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PHOX2A
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen All enteric nervous system cells evolve from the neural crest, Both Phox2a and Phox2b are crucial for the regulation of endogenous tyrosine hydroxylase and dopamine-beta hydroxylase, In addition, In contrast, Phox2 proteins are sufficient to promote sympathetic neuron generation, Phox2a controls only the differentiation of the main noradrenergic center of the brain, Phox2b is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain, The cells that begin to differentiate along a neuronal lineage continue to express Phox2b, The gene which encodes Phox2a maps to human chromosome 11q13, and all cells that are undifferentiated initially express Phox2b, and begin to express Phox2a, paired-homeodomain transcription factors that are necessary for neuronal differentiation throughout the developing sympathetic, parasympathetic and enteric ganglia, the locus ceruleus, which are transiently expressed in neural crest cells, 3-q13, 4, Phox2a (also designated Arix1) and Phox2b are closely related
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ARIX, ARIX 1 homeodomain protein, ARIX1 homeodomain protein, Aristaless homeobox gene homolog Drosophila, Aristaless homeobox homolog, Aristaless homeobox protein homolog, Arix homeodomain protein, CFEOM 2, CFEOM2, FEOM 2, FEOM2, Fibrosis of extraocular muscles congenital 2 autosomal recessive, MGC52227, NCAM 2, NCAM2, PHOX 2A, PHX2A_HUMAN, Paired like aristaless Homeobox 2A, Paired like homeobox 2a, Paired mesoderm homeobox 2a, Paired mesoderm homeobox protein 2A, Paired-like homeobox 2A, Phox2, Phox2a, Pmx 2a, Pmx2, Pmx2a, Aristaless homeobox Drosophila fibrosis of extraocular muscles congenital 2 autosomal recessive
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPHOX2A/CFEOM2
Short namePHOX2A/CFEOM2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePHOX2A/CFEOM2 (Antibody to)
Alternative techniqueantibodies
Identity 691
Gene PHOX2A
Long gene name paired like homeobox 2a
Synonyms gene ARIX FEOM2
Synonyms gene name 2, aristaless (Drosophila) homeobox, aristaless homeobox (Drosophila), autosomal recessive paired-like (aristaless) homeobox 2a , congenital, fibrosis of extraocular muscles
Synonyms PMX2A CFEOM2
Locus 11q13, 4
Discovery year 1995-12-11
GenBank acession AF022722
Entrez gene record 401
Pubmed identfication 8661014 11600883
RefSeq identity NM_005169
Classification PRD class homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000167899

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