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PHOX2A/CFEOM2 Antibody, Biotin Conjugated

PHOX2A/CFEOM2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, PHOX2A/CFEOM2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPHOX2A/CFEOM2
SpecificityThis is a highly specific antibody against PHOX2A/CFEOM2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human PHOX2A
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background All enteric nervous system cells evolve from the neural crest, Both Phox2a and Phox2b are crucial for the regulation of endogenous tyrosine hydroxylase and dopamine-beta hydroxylase, In addition, In contrast, Phox2 proteins are sufficient to promote sympathetic neuron generation, Phox2a controls only the differentiation of the main noradrenergic center of the brain, Phox2b is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain, The cells that begin to differentiate along a neuronal lineage continue to express Phox2b, The gene which encodes Phox2a maps to human chromosome 11q13, and all cells that are undifferentiated initially express Phox2b, and begin to express Phox2a, paired-homeodomain transcription factors that are necessary for neuronal differentiation throughout the developing sympathetic, parasympathetic and enteric ganglia, the locus ceruleus, which are transiently expressed in neural crest cells, 3-q13, 4, Phox2a (also designated Arix1) and Phox2b are closely related
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms PMX2A CFEOM2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPHOX2A/CFEOM2 Conjugated
Short name Conjugated, PHOX2A/CFEOM2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, PHOX2A/CFEOM2 (Antibody to)
Alternative techniqueantibodies
Identity 691
Gene PHOX2A
Long gene name paired like homeobox 2a
Synonyms gene ARIX FEOM2
Synonyms gene name 2, aristaless (Drosophila) homeobox, aristaless homeobox (Drosophila), autosomal recessive paired-like (aristaless) homeobox 2a , congenital, fibrosis of extraocular muscles
Locus 11q13, 4
Discovery year 1995-12-11
GenBank acession AF022722
Entrez gene record 401
Pubmed identfication 8661014 11600883
RefSeq identity NM_005169
Classification PRD class homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000167899

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