Name : PHOX2A/CFEOM2 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5159671518
| Long name | FITC Conjugated, PHOX2A/CFEOM2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PHOX2A/CFEOM2 |
| Specificity | This is a highly specific antibody against PHOX2A/CFEOM2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human PHOX2A |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | All enteric nervous system cells evolve from the neural crest, Both Phox2a and Phox2b are crucial for the regulation of endogenous tyrosine hydroxylase and dopamine-beta hydroxylase, In addition, In contrast, Phox2 proteins are sufficient to promote sympathetic neuron generation, Phox2a controls only the differentiation of the main noradrenergic center of the brain, Phox2b is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain, The cells that begin to differentiate along a neuronal lineage continue to express Phox2b, The gene which encodes Phox2a maps to human chromosome 11q13, and all cells that are undifferentiated initially express Phox2b, and begin to express Phox2a, paired-homeodomain transcription factors that are necessary for neuronal differentiation throughout the developing sympathetic, parasympathetic and enteric ganglia, the locus ceruleus, which are transiently expressed in neural crest cells, 3-q13, 4, Phox2a (also designated Arix1) and Phox2b are closely related |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | PMX2A CFEOM2 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PHOX2A/CFEOM2 Conjugated |
| Short name | FITC Conjugated, PHOX2A/CFEOM2 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, PHOX2A/CFEOM2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 691 |
| Gene | PHOX2A |
| Long gene name | paired like homeobox 2a |
| Synonyms gene | ARIX FEOM2 |
| Synonyms gene name | 2, aristaless (Drosophila) homeobox, aristaless homeobox (Drosophila), autosomal recessive paired-like (aristaless) homeobox 2a , congenital, fibrosis of extraocular muscles |
| Locus | 11q13, 4 |
| Discovery year | 1995-12-11 |
| GenBank acession | AF022722 |
| Entrez gene record | 401 |
| Pubmed identfication | 8661014 11600883 |
| RefSeq identity | NM_005169 |
| Classification | PRD class homeoboxes and pseudogenes |
| Havana BLAST/BLAT | OTTHUMG00000167899 |