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PHYHIP Antibody, FITC Conjugated

PHYHIP Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, PHYHIP Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPHYHIP
SpecificityThis is a highly specific antibody against PHYHIP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human PHYHIP
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background In transgenic mice, PAHX, PHYHIP also interacts with Dyrk1A, PHYHIP interacts with the Refsum disease gene product, Significantly, a protein that that is overexpressed in brain of Down-syndrome patients, breast and several other types of cancers, indicating that PHYHIP may play a role in the CNS deficits of Refsum disease, neurologic damage and peripheral neuropathies, overexpression of PHYHIP in heart results in tachycardia and tachyarrhythmia, small intestine and ovary, the gene encoding PHYHIP is localized to a region of the short arm of human chromosome 8 that is frequently found deleted in prostate, therefore PHYHIP may participate in some of the neurological abnormalities of Down syndrome, which is characterized by cerebellar degeneration, with weak expression in ovary, PHYHIP (Phytanoyl-CoA hydroxylase-interacting protein) is a 330 amino acid protein that is strongly expressed in brain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms KIAA0273 PAHX-AP
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPHYHIP Conjugated
Short name FITC Conjugated, PHYHIP Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PHYHIP (Antibody to)
Alternative techniqueantibodies
Identity 16865
Gene PHYHIP
Long gene name phytanoyl-CoA 2-hydroxylase interacting protein
Synonyms gene DYRK1AP3
Synonyms gene name phytanoyl-CoA hydroxylase interacting protein DYRK1A interacting protein 3
Locus 8p21, 3
Discovery year 2001-11-16
GenBank acession D87463
Entrez gene record 9796
Pubmed identfication 9039502 10686344
RefSeq identity NM_014759
Havana BLAST/BLAT OTTHUMG00000163776

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