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PI3 Kinase p110 delta antibody, ALEXA FLUOR 488

PI3 Kinase p110 delta antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, PI3 Kinase p110 delta antibody
Also known asAnti-PI3 Kinase p110 delta PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPI3 Kinase p110 delta
SpecificityThis is a highly specific antibody against PI3 Kinase p110 delta
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PI3 Kinase p110 delta
Gene ID Number5293
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Activation by TCR leads to antigen-dependent memory T-cell migration and retention to antigenic tissues, CCR7 and S1PR1 and antigen dependent recruitment of T-cells, Contributes to T-helper cell expansion and differentiation, Have a role in NK cell maturation and cytokine production, Have important roles in mast-cell development and mast cell mediated allergic response, Involved in B-cell chemotaxis in response to CXCL13 and sphingosine 1-phosphate (S1P), Involved in stem cell factor (SCF)-mediated proliferation, Involved in the antigen presentation function of B-cells, Mediates B-cell proliferation response to anti-IgM, Mediates TCR signaling events at the immune synapse, Mediates immune responses, PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, Participates in NK cell receptor activation, Plays a role in B-cell development, Promotes cytokine production in response to TLR4 and TLR9, Required for B-cell receptor (BCR) signaling, Required for T-cell migration mediated by homing receptors SELL/CD62L, Required for T-cell receptor (TCR) signaling, Required for antibody class switch mediated by TLR9, Required for proliferation, Together with PIK3CG is involved in natural killer (NK) cell development and migration towards the sites of inflammation, Together with PIK3CG is involved in neutrophil chemotaxis and extravasation, Together with PIK3CG participates in T-cell development, Together with PIK3CG participates in neutrophil respiratory burst, activating signaling cascades involved in cell growth, adhesion and migration, and function, anti-CD40 and IL4 stimulation, effector and memory T-cells, including AKT1 and PDPK1, migration, motility and morphology, proliferation, proliferation, signaling and cytokine production of naive, survival, 4, 5)P2 (Phosphatidylinositol 4, 5-bisphosphate) to generate phosphatidylinositol 3, 5-trisphosphate (PIP3), Phosphoinositide-3-kinase (PI3K) that phosphorylates PftdIns(4
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms ESI SKALP ELAFIN WAP3 WFDC14 cementoin
Properties Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PI3 Kinase p110 delta antibody, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
French translationanticorps
Gene targetPI3 Kinase p110 delta
Short namePI3 Kinase p110 delta antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, PI3 phosphorylation catalyst p110 delta (Antibody to)
Alternative techniqueantibodies
Identity 8947
Gene PI3
Long gene name peptidase inhibitor 3
Synonyms gene name protease inhibitor 3, skin-derived , skin-derived (SKALP) peptidase inhibitor 3
Synonyms name skin-derived antileukoproteinase trappin-2
Locus 20q13, 12
Discovery year 1993-07-27
GenBank acession D13156
Entrez gene record 5266
Pubmed identfication 8287685 12206714
RefSeq identity NM_002638
Classification WAP four-disulfide core domain containing
Havana BLAST/BLAT OTTHUMG00000032567

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