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PI3 Kinase p110 delta antibody, FITC Conjugated

PI3 Kinase p110 delta antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, PI3 Kinase p110 delta antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPI3 Kinase p110 delta
SpecificityThis is a highly specific antibody against PI3 Kinase p110 delta
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human PI3 Kinase p110 delta
Gene ID number5293
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activation by TCR leads to antigen-dependent memory T-cell migration and retention to antigenic tissues, CCR7 and S1PR1 and antigen dependent recruitment of T-cells, Contributes to T-helper cell expansion and differentiation, Have a role in NK cell maturation and cytokine production, Have important roles in mast-cell development and mast cell mediated allergic response, Involved in B-cell chemotaxis in response to CXCL13 and sphingosine 1-phosphate (S1P), Involved in stem cell factor (SCF)-mediated proliferation, Involved in the antigen presentation function of B-cells, Mediates B-cell proliferation response to anti-IgM, Mediates TCR signaling events at the immune synapse, Mediates immune responses, PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, Participates in NK cell receptor activation, Plays a role in B-cell development, Promotes cytokine production in response to TLR4 and TLR9, Required for B-cell receptor (BCR) signaling, Required for T-cell migration mediated by homing receptors SELL/CD62L, Required for T-cell receptor (TCR) signaling, Required for antibody class switch mediated by TLR9, Required for proliferation, Together with PIK3CG is involved in natural killer (NK) cell development and migration towards the sites of inflammation, Together with PIK3CG is involved in neutrophil chemotaxis and extravasation, Together with PIK3CG participates in T-cell development, Together with PIK3CG participates in neutrophil respiratory burst, activating signaling cascades involved in cell growth, adhesion and migration, and function, anti-CD40 and IL4 stimulation, effector and memory T-cells, including AKT1 and PDPK1, migration, motility and morphology, proliferation, proliferation, signaling and cytokine production of naive, survival, 4, 5)P2 (Phosphatidylinositol 4, 5-bisphosphate) to generate phosphatidylinositol 3, 5-trisphosphate (PIP3), Phosphoinositide-3-kinase (PI3K) that phosphorylates PftdIns(4
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms ESI SKALP ELAFIN WAP3 WFDC14 cementoin
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS
French translationanticorps
Gene targetPI3 Kinase p110 delta Conjugated
Short name FITC Conjugated, PI3 Kinase p110 delta antibody
Technique Fluorescein, antibody Conjugates, FITC
LabelFITC
Alternative name fluorecein coupled, PI3 phosphorylation catalyst p110 delta (Antibody to)
Alternative techniqueantibodies
Identity 8947
Gene PI3
Long gene name peptidase inhibitor 3
Synonyms gene name protease inhibitor 3, skin-derived , skin-derived (SKALP) peptidase inhibitor 3
Synonyms name skin-derived antileukoproteinase trappin-2
Locus 20q13, 12
Discovery year 1993-07-27
GenBank acession D13156
Entrez gene record 5266
Pubmed identfication 8287685 12206714
RefSeq identity NM_002638
Classification WAP four-disulfide core domain containing
Havana BLAST/BLAT OTTHUMG00000032567

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