PI3K Antibody

PI3K Antibody size: 0.1mg 406

Price 406

Size 0.1mg

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Category	Antibody
Concentration	2ml sterile DI water, 5mg/ml if reconstituted with 0
Form	Antigen affinity purified
Conjugation	Unconjugated
Clone	Polyclonal antibody
Recognised antigen	PI3K
Host animal	Rabbit (Oryctolagus cuniculus)
Clonality	Polyclonal (rabbit origin)
Species reactivity	Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications	WB
Recommended dilutions	5-1ug/ml, Western blot: 0
Notes	Titration of the PI3K antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented use	This PI3K antibodyis to be used only for research purposes and not for diagnostics
Gene ID #	5290
Purity	Antigen affinity
Description	In addition to that, It has been found to be oncogenic and has been implicated in cervical cancers, PIK3CA (alpha subunit) mutations in breast cancer may be a predictive marker to guide the selection of patients who would benefit from mTOR inhibitor therapy, PtdIns4P andPtdIns(4, Recent evidence has shown that the gene is mutated in a range of human cancers, The protein encoded by the PIK3CA gene represents the catalytic subunit, also called PI3K, indicating power and promise of Molecular Pathological Epidemiology (MPE) approach as well as a complex interaction within the tumor microenvironment in this phenomenon, is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit, the presence of mutations may predict response to aspirin therapy for colorectal cancer, which uses ATP to phosphorylate phosphatidylinositols (PtdIns), 5)P2, 5-bisphosphate 3-kinase, Phosphatidylinositol-4
Immunogen	Human partial recombinant protein (AA 936-1068) from the p110 catalytic subunit was used as the immunogen for this PI3K antibody
Storage	Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PI3K antibody can be stored for up to one month at 4oC, After reconstitution
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target	PI3K
Short name	PI3K Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	PI3K (Antibody to)
Alternative technique	antibodies
Identity	8975
Gene	PIK3CA
Long gene name	phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit alpha
Synonyms gene name	alpha polypeptide phosphatidylinositol-4, catalytic, catalytic subunit alpha , phosphoinositide-3-kinase, 5-bisphosphate 3-kinase
Synonyms	PI3K
Locus	3q26, 32
Discovery year	1994-07-15
Entrez gene record	5290
Pubmed identfication	1322797
Classification	Phosphatidylinositol 3-kinase subunits
Havana BLAST/BLAT	OTTHUMG00000157311
Locus Specific Databases	LRG_310

PI3K Antibody

PI3K Antibody size: 0.1mg 406

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