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PI3KCA Antibody, ALEXA FLUOR 594

PI3KCA Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, PI3KCA Polyclonal Antibody
Also known asAnti-PI3KCA PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPI3KCA
SpecificityThis is a highly specific antibody against PI3KCA
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1010-1050/1068
Subcellular location Membrane bound, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PI3KCA
Gene ID Number5290
Swiss ProtP42336
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen EIF4EBP1 and HRAS, Essential in endothelial cell migration during vascular development through VEGFA signaling, Has also serine-protein kinase activity: phosphorylates PIK3R1 (p85alpha regulatory subunit), IGF1, Involved in signaling via insulin-receptor substrate (IRS) proteins, Involved in the activation of AKT1 upon stimulation by receptor tyrosine kinases ligands such as EGF, PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, Participates in cardiomyogenesis in embryonic stem cells through a AKT1 pathway, Participates in cellular signaling in response to various growth factors, Participates in vasculogenesis in embryonic stem cells through PDK1 and protein kinase C pathway, PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4, Regulates invadopodia formation in breast cancer cells through the PDPK1-AKT1 pathway, Required for lymphatic vasculature development, VEGFA and PDGF, activating signaling cascades involved in cell growth, but not by PDGF, including AKT1 and PDPK1, insulin, motility and morphology, possibly by binding to RAS and by activation by EGF and FGF2, possibly by regulating RhoA activity, proliferation, survival, 4, 5)P2 (Phosphatidylinositol 4, 5-bisphosphate) to generate phosphatidylinositol 3, 5-trisphosphate (PIP3), Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms CLOVE, CWS5, MCAP, MCMTC, PI3-kinase subunit alpha, PI3K, PI3K-alpha, PI3Kalpha, PIK3CA, Phosphatidylinositol 4, Phosphatidylinositol 4, Phosphoinositide-3-kinase catalytic alpha polypeptide, PtdIns-3-kinase subunit alpha, PtdIns-3-kinase subunit p11-alpha, Serine/threonine protein kinase PIK3CA, p11-alpha, p11alpha, 5-bisphosphate 3-kinase 11 kDa catalytic subunit alpha, 5-bisphosphate 3-kinase catalytic subunit alpha isoform, MCM
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetPI3KCA
Short namePI3KCA Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, PI3KCA (Antibody to)
Alternative techniqueantibodies

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