Name : PIASg Antibody (PIAS4)
Supplier : NJS POLY
Price :389
SKU : GEN1583066496
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | PIASg (PIAS4) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 5-1ug/ml, Western blot: 0 |
| Notes | Titration of the PIASg antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This PIASg antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q8N2W9 |
| Purity | Antigen affinity |
| Description | PIASg functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, This gene involved in gene silencing, This gene is mapped to 19p13, This gene plays a crucial role as a transcriptional coregulation in various cellular pathways, and as a SUMO-tethering factor, including the STAT pathway, stabilizing the interaction between UBE2I and the substrate, the Wnt pathway and the steroid hormone signaling pathway, the p53/TP53 pathway, 3, Protein inhibitor of activated STAT protein 4 (PIAS4) or Protein inhibitor of activated STAT protein gamma (PIASg or PIASy) is an enzyme that in humans is encoded by the PIAS4 gene |
| Immunogen | mouse and rat), An amino acid sequence from the C-terminus of human E3 SUMO-protein ligase PIASg (HPELCKALVKEKLRLD) was used as the immunogen for this PIASg antibody (100% homologous in human |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PIASg antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | PIASg (PIAS4) |
| Short name | PIASg Antibody (PIAS4) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | PIASg (Antibody to) (PIAS4) |
| Alternative technique | antibodies |
| Identity | 17002 |
| Gene | PIAS4 |
| Long gene name | protein inhibitor of activated STAT 4 |
| Synonyms | Piasg PIASY FLJ12419 ZMIZ6 |
| Synonyms name | MIZ-type containing 6 , zinc finger |
| Locus | 19p13, 3 |
| Discovery year | 2004-06-02 |
| GenBank acession | AF077952 |
| Entrez gene record | 51588 |
| Pubmed identfication | 9724754 |
| RefSeq identity | NM_015897 |
| Classification | Zinc fingers MIZ-type |
| Havana BLAST/BLAT | OTTHUMG00000181759 |