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PIK3R1(Tyr467) Antibody, FITC Conjugated

PIK3R1(Tyr467) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, PIK3R1(Tyr467) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPIK3R1 Tyr467
SpecificityThis is a highly specific antibody against PIK3R1 Tyr467
ModificationPhosphorylation
Modification siteTyr467
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PIK3R1 around the phosphorylation site of Tyr467 [RL(p-Y)EE]
Gene ID number5295
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 4, 5-triphosphate in response to receptor activation in many signal transduction pathways, Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e, p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane, p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues, p85 alpha), The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, g
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms GRB1 p85-ALPHA p85
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPIK3R1(Tyr467) Conjugated
Short name FITC Conjugated, PIK3R1(Tyr467) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PIK3R1(Tyr467) (Antibody to)
Alternative techniqueantibodies
Identity 8979
Gene PIK3R1
Long gene name phosphoinositide-3-kinase regulatory subunit 1
Synonyms gene name phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Synonyms name phosphoinositide-3-kinase regulatory subunit alpha
Locus 5q13, 1
Discovery year 1992-12-08
GenBank acession M61906
Entrez gene record 5295
Pubmed identfication 1314371 18387942
RefSeq identity NM_181504
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000131251
Locus Specific Databases SH2base: Database for pathogenic SH2 domain mutations LRG_453

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